An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate

An observational study on 22 patients presenting with acute limb ischemia and SARS-CoV-2 infection, and without any other embolic risk factors, was performed. All patients were classified according to Rutherford classification for acute limb ischemia. The primary goal of this study was to assess the...

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Autores principales: Sorin Barac, Roxana Ramona Onofrei, Petru Vlad Neagoe, Alexandra Ioana Popescu, Stelian Pantea, Andreea Luciana Rață
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Lenguaje:EN
Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:a4fd70e819ce410bbdb7a444e6e294a02021-11-11T17:42:47ZAn Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate10.3390/jcm102150832077-0383https://doaj.org/article/a4fd70e819ce410bbdb7a444e6e294a02021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/5083https://doaj.org/toc/2077-0383An observational study on 22 patients presenting with acute limb ischemia and SARS-CoV-2 infection, and without any other embolic risk factors, was performed. All patients were classified according to Rutherford classification for acute limb ischemia. The primary goal of this study was to assess the risk of amputation in these patients after revascularization procedures. The secondary goal was to find the correlation between acute limb ischemia (ALI) severity, patient comorbidities, risk of death, and the association of SARS-CoV-2 infection. The patients were treated by open surgery (18 patients—81.81%) or by the means of endovascular techniques (four patients—18.18%). The amputation-free survival rate was 81.81% in hospital and 86.36% at 1-month follow-up. In this study, the presence of SARS-CoV-2 infection did not influence the amputation-free survival rate: it was only the risk factor for the arterial thrombosis and the trigger for the acute ischemic event. The application of the standard treatment—open surgery or endovascular revascularization—in patients with acute limb ischemia and SARS-CoV-2 infection represents the key to success for lower limb salvage.Sorin BaracRoxana Ramona OnofreiPetru Vlad NeagoeAlexandra Ioana PopescuStelian PanteaAndreea Luciana RațăMDPI AGarticleSARS-CoV-2 infectionacute limb ischemiaamputation-free survival rateMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5083, p 5083 (2021)
institution DOAJ
collection DOAJ
language EN
topic SARS-CoV-2 infection
acute limb ischemia
amputation-free survival rate
Medicine
R
spellingShingle SARS-CoV-2 infection
acute limb ischemia
amputation-free survival rate
Medicine
R
Sorin Barac
Roxana Ramona Onofrei
Petru Vlad Neagoe
Alexandra Ioana Popescu
Stelian Pantea
Andreea Luciana Rață
An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate
description An observational study on 22 patients presenting with acute limb ischemia and SARS-CoV-2 infection, and without any other embolic risk factors, was performed. All patients were classified according to Rutherford classification for acute limb ischemia. The primary goal of this study was to assess the risk of amputation in these patients after revascularization procedures. The secondary goal was to find the correlation between acute limb ischemia (ALI) severity, patient comorbidities, risk of death, and the association of SARS-CoV-2 infection. The patients were treated by open surgery (18 patients—81.81%) or by the means of endovascular techniques (four patients—18.18%). The amputation-free survival rate was 81.81% in hospital and 86.36% at 1-month follow-up. In this study, the presence of SARS-CoV-2 infection did not influence the amputation-free survival rate: it was only the risk factor for the arterial thrombosis and the trigger for the acute ischemic event. The application of the standard treatment—open surgery or endovascular revascularization—in patients with acute limb ischemia and SARS-CoV-2 infection represents the key to success for lower limb salvage.
format article
author Sorin Barac
Roxana Ramona Onofrei
Petru Vlad Neagoe
Alexandra Ioana Popescu
Stelian Pantea
Andreea Luciana Rață
author_facet Sorin Barac
Roxana Ramona Onofrei
Petru Vlad Neagoe
Alexandra Ioana Popescu
Stelian Pantea
Andreea Luciana Rață
author_sort Sorin Barac
title An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate
title_short An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate
title_full An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate
title_fullStr An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate
title_full_unstemmed An Observational Study on Patients with Acute Limb Ischemia and SARS-CoV-2 Infection: Early and Late Results in Limb Salvage Rate
title_sort observational study on patients with acute limb ischemia and sars-cov-2 infection: early and late results in limb salvage rate
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/a4fd70e819ce410bbdb7a444e6e294a0
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