Short Communication: Antibacterial effect of red betel (Piper crocatum) extract in combination with vancomycin against Staphylococcus aureus

Abstract. Hartini YS, Nugroho LH. 2020. Short Communication: Antibacterial effect of red betel (Piper crocatum) extract in combination with vancomycin against Staphylococcus aureus. Biodiversitas 21: 3271-3274. The occurrence of bacterial resistance to a single antimicrobial compound has prompted...

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Autores principales:	Yustina Sri Hartini, Laurentius Hartanto Nugroho
Formato:	article
Lenguaje:	EN
Publicado:	MBI & UNS Solo 2020
Materias:	piper crocatum, vancomycin, synergistic antibacterial, staphylococcus aureus Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/a501a0146def4719a34a1cd22f548927
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spelling	oai:doaj.org-article:a501a0146def4719a34a1cd22f5489272021-11-22T00:40:51ZShort Communication: Antibacterial effect of red betel (Piper crocatum) extract in combination with vancomycin against Staphylococcus aureus1412-033X2085-472210.13057/biodiv/d210750https://doaj.org/article/a501a0146def4719a34a1cd22f5489272020-06-01T00:00:00Zhttps://smujo.id/biodiv/article/view/5818https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Abstract. Hartini YS, Nugroho LH. 2020. Short Communication: Antibacterial effect of red betel (Piper crocatum) extract in combination with vancomycin against Staphylococcus aureus. Biodiversitas 21: 3271-3274. The occurrence of bacterial resistance to a single antimicrobial compound has prompted the search for antimicrobials in the form of compound combinations. The current study was performed to show the antibacterial effect of red betel (Piper crocatum Ruiz & Pav.) in combination with vancomycin against Staphylococcus aureus. The combination of the antibacterial compounds from plant with the antibacterial drug was expected to increase antibacterial activity resulted in the reduction of resistance. The interaction effect of extract and antibiotic combination was performed using the microdilution checkerboard method. The combination of red betel extract with vancomycin showed significantly (p < 0.05) greater inhibition growth of S. aureus compared to red betel or vancomycin alone. The addition of red betel extract to vancomycin reduced Minimum Inhibitory Concentration (MIC) vancomycin to be a-4 fold reduction against S. aureus. There was a synergistic effect of the red betel extract in combination with vancomycin against S. aureus. It is the potential result for future research on the infectious treatment of S. aureus resistant to vancomycin.Yustina Sri HartiniLaurentius Hartanto NugrohoMBI & UNS Soloarticlepiper crocatum, vancomycin, synergistic antibacterial, staphylococcus aureusBiology (General)QH301-705.5ENBiodiversitas, Vol 21, Iss 7 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	piper crocatum, vancomycin, synergistic antibacterial, staphylococcus aureus Biology (General) QH301-705.5
spellingShingle	piper crocatum, vancomycin, synergistic antibacterial, staphylococcus aureus Biology (General) QH301-705.5 Yustina Sri Hartini Laurentius Hartanto Nugroho Short Communication: Antibacterial effect of red betel (Piper crocatum) extract in combination with vancomycin against Staphylococcus aureus
description	Abstract. Hartini YS, Nugroho LH. 2020. Short Communication: Antibacterial effect of red betel (Piper crocatum) extract in combination with vancomycin against Staphylococcus aureus. Biodiversitas 21: 3271-3274. The occurrence of bacterial resistance to a single antimicrobial compound has prompted the search for antimicrobials in the form of compound combinations. The current study was performed to show the antibacterial effect of red betel (Piper crocatum Ruiz & Pav.) in combination with vancomycin against Staphylococcus aureus. The combination of the antibacterial compounds from plant with the antibacterial drug was expected to increase antibacterial activity resulted in the reduction of resistance. The interaction effect of extract and antibiotic combination was performed using the microdilution checkerboard method. The combination of red betel extract with vancomycin showed significantly (p < 0.05) greater inhibition growth of S. aureus compared to red betel or vancomycin alone. The addition of red betel extract to vancomycin reduced Minimum Inhibitory Concentration (MIC) vancomycin to be a-4 fold reduction against S. aureus. There was a synergistic effect of the red betel extract in combination with vancomycin against S. aureus. It is the potential result for future research on the infectious treatment of S. aureus resistant to vancomycin.
format	article
author	Yustina Sri Hartini Laurentius Hartanto Nugroho
author_facet	Yustina Sri Hartini Laurentius Hartanto Nugroho
author_sort	Yustina Sri Hartini
title	Short Communication: Antibacterial effect of red betel (Piper crocatum) extract in combination with vancomycin against Staphylococcus aureus
title_short	Short Communication: Antibacterial effect of red betel (Piper crocatum) extract in combination with vancomycin against Staphylococcus aureus
title_full	Short Communication: Antibacterial effect of red betel (Piper crocatum) extract in combination with vancomycin against Staphylococcus aureus
title_fullStr	Short Communication: Antibacterial effect of red betel (Piper crocatum) extract in combination with vancomycin against Staphylococcus aureus
title_full_unstemmed	Short Communication: Antibacterial effect of red betel (Piper crocatum) extract in combination with vancomycin against Staphylococcus aureus
title_sort	short communication: antibacterial effect of red betel (piper crocatum) extract in combination with vancomycin against staphylococcus aureus
publisher	MBI & UNS Solo
publishDate	2020
url	https://doaj.org/article/a501a0146def4719a34a1cd22f548927
work_keys_str_mv	AT yustinasrihartini shortcommunicationantibacterialeffectofredbetelpipercrocatumextractincombinationwithvancomycinagainststaphylococcusaureus AT laurentiushartantonugroho shortcommunicationantibacterialeffectofredbetelpipercrocatumextractincombinationwithvancomycinagainststaphylococcusaureus
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Short Communication: Antibacterial effect of red betel (Piper crocatum) extract in combination with vancomycin against Staphylococcus aureus

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