Defining functional interactions during biogenesis of epithelial junctions

Formation and reinforcement of E-cadherin-mediated adhesion depends on intracellular trafficking and interactions with the actin cytoskeleton, but how these are coordinated is not known. Here the authors conduct a focused phenotypic screen to identify new pathways regulating cell–cell junction homeo...

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Auteurs principaux:	J. C. Erasmus, S. Bruche, L. Pizarro, N. Maimari, T. Poggioli, C. Tomlinson, J. Lees, I. Zalivina, A. Wheeler, A. Alberts, A. Russo, V. M. M. Braga
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2016
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/a517aedc4fcf47fbb3d4995cad4e055b
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spelling	oai:doaj.org-article:a517aedc4fcf47fbb3d4995cad4e055b2021-12-02T17:32:36ZDefining functional interactions during biogenesis of epithelial junctions10.1038/ncomms135422041-1723https://doaj.org/article/a517aedc4fcf47fbb3d4995cad4e055b2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13542https://doaj.org/toc/2041-1723Formation and reinforcement of E-cadherin-mediated adhesion depends on intracellular trafficking and interactions with the actin cytoskeleton, but how these are coordinated is not known. Here the authors conduct a focused phenotypic screen to identify new pathways regulating cell–cell junction homeostasis.J. C. ErasmusS. BrucheL. PizarroN. MaimariT. PoggioliC. TomlinsonJ. LeesI. ZalivinaA. WheelerA. AlbertsA. RussoV. M. M. BragaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q J. C. Erasmus S. Bruche L. Pizarro N. Maimari T. Poggioli C. Tomlinson J. Lees I. Zalivina A. Wheeler A. Alberts A. Russo V. M. M. Braga Defining functional interactions during biogenesis of epithelial junctions
description	Formation and reinforcement of E-cadherin-mediated adhesion depends on intracellular trafficking and interactions with the actin cytoskeleton, but how these are coordinated is not known. Here the authors conduct a focused phenotypic screen to identify new pathways regulating cell–cell junction homeostasis.
format	article
author	J. C. Erasmus S. Bruche L. Pizarro N. Maimari T. Poggioli C. Tomlinson J. Lees I. Zalivina A. Wheeler A. Alberts A. Russo V. M. M. Braga
author_facet	J. C. Erasmus S. Bruche L. Pizarro N. Maimari T. Poggioli C. Tomlinson J. Lees I. Zalivina A. Wheeler A. Alberts A. Russo V. M. M. Braga
author_sort	J. C. Erasmus
title	Defining functional interactions during biogenesis of epithelial junctions
title_short	Defining functional interactions during biogenesis of epithelial junctions
title_full	Defining functional interactions during biogenesis of epithelial junctions
title_fullStr	Defining functional interactions during biogenesis of epithelial junctions
title_full_unstemmed	Defining functional interactions during biogenesis of epithelial junctions
title_sort	defining functional interactions during biogenesis of epithelial junctions
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/a517aedc4fcf47fbb3d4995cad4e055b
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Defining functional interactions during biogenesis of epithelial junctions

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