Combinatorial modeling of chromatin features quantitatively predicts DNA replication timing in Drosophila.
In metazoans, each cell type follows a characteristic, spatio-temporally regulated DNA replication program. Histone modifications (HMs) and chromatin binding proteins (CBPs) are fundamental for a faithful progression and completion of this process. However, no individual HM is strictly indispensable...
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| Autores principales: | , |
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| Formato: | article |
| Lenguaje: | EN |
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Public Library of Science (PLoS)
2014
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| Acceso en línea: | https://doaj.org/article/a51adfc34e74418290baee6ef68c5a6d |
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