Evaluation of Brain Activity Using Near-infrared Spectroscopy in Inflammatory Bowel Disease Patients

Abstract Depression is implicated as a risk factor for the recurrence of inflammatory bowel disease (IBD). Near-infrared spectroscopy (NIRS) and brain-derived neurotrophic factor (BDNF) are useful tools for evaluation of brain activity and a depressive state, respectively. The aim of this study was...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Tatsuo Fujiwara, Soichi Kono, Kyoko Katakura, Kazumichi Abe, Atsushi Takahashi, Naohiko Gunji, Aki Yokokawa, Kazumasa Kawashima, Rieko Suzuki, Akira Wada, Itaru Miura, Hirooki Yabe, Hiromasa Ohira
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a51cf175a8914196a14f71f32c3bfd0f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a51cf175a8914196a14f71f32c3bfd0f
record_format	dspace
spelling	oai:doaj.org-article:a51cf175a8914196a14f71f32c3bfd0f2021-12-02T15:08:55ZEvaluation of Brain Activity Using Near-infrared Spectroscopy in Inflammatory Bowel Disease Patients10.1038/s41598-017-18897-42045-2322https://doaj.org/article/a51cf175a8914196a14f71f32c3bfd0f2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-18897-4https://doaj.org/toc/2045-2322Abstract Depression is implicated as a risk factor for the recurrence of inflammatory bowel disease (IBD). Near-infrared spectroscopy (NIRS) and brain-derived neurotrophic factor (BDNF) are useful tools for evaluation of brain activity and a depressive state, respectively. The aim of this study was to clarify the association between brain activity or depressive symptoms and IBD using NIRS and BDNF. This study included 36 ulcerative colitis (UC) patients, 32 Crohn’s disease (CD) patients, and 17 healthy controls (HC). Center for Epidemiologic Studies Depression Scale (CES-D) scores were determined, NIRS was performed, and serum BDNF levels were measured in all subjects. NIRS showed that the mean oxygenated hemoglobin concentration was significantly lower in the frontal lobe in the UC group than in the HC group (HC 167 ± 106 vs. UC 83.1 ± 85.3, p < 0.05). No significant difference was seen between the HC and CD groups. There were also no significant differences in CED-D scores and BDNF levels among the groups. Changes in the NIRS values of the UC group may indicate decreased brain activity and a fundamental difference between UC and CD, which are often lumped together as two types of IBD.Tatsuo FujiwaraSoichi KonoKyoko KatakuraKazumichi AbeAtsushi TakahashiNaohiko GunjiAki YokokawaKazumasa KawashimaRieko SuzukiAkira WadaItaru MiuraHirooki YabeHiromasa OhiraNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Tatsuo Fujiwara Soichi Kono Kyoko Katakura Kazumichi Abe Atsushi Takahashi Naohiko Gunji Aki Yokokawa Kazumasa Kawashima Rieko Suzuki Akira Wada Itaru Miura Hirooki Yabe Hiromasa Ohira Evaluation of Brain Activity Using Near-infrared Spectroscopy in Inflammatory Bowel Disease Patients
description	Abstract Depression is implicated as a risk factor for the recurrence of inflammatory bowel disease (IBD). Near-infrared spectroscopy (NIRS) and brain-derived neurotrophic factor (BDNF) are useful tools for evaluation of brain activity and a depressive state, respectively. The aim of this study was to clarify the association between brain activity or depressive symptoms and IBD using NIRS and BDNF. This study included 36 ulcerative colitis (UC) patients, 32 Crohn’s disease (CD) patients, and 17 healthy controls (HC). Center for Epidemiologic Studies Depression Scale (CES-D) scores were determined, NIRS was performed, and serum BDNF levels were measured in all subjects. NIRS showed that the mean oxygenated hemoglobin concentration was significantly lower in the frontal lobe in the UC group than in the HC group (HC 167 ± 106 vs. UC 83.1 ± 85.3, p < 0.05). No significant difference was seen between the HC and CD groups. There were also no significant differences in CED-D scores and BDNF levels among the groups. Changes in the NIRS values of the UC group may indicate decreased brain activity and a fundamental difference between UC and CD, which are often lumped together as two types of IBD.
format	article
author	Tatsuo Fujiwara Soichi Kono Kyoko Katakura Kazumichi Abe Atsushi Takahashi Naohiko Gunji Aki Yokokawa Kazumasa Kawashima Rieko Suzuki Akira Wada Itaru Miura Hirooki Yabe Hiromasa Ohira
author_facet	Tatsuo Fujiwara Soichi Kono Kyoko Katakura Kazumichi Abe Atsushi Takahashi Naohiko Gunji Aki Yokokawa Kazumasa Kawashima Rieko Suzuki Akira Wada Itaru Miura Hirooki Yabe Hiromasa Ohira
author_sort	Tatsuo Fujiwara
title	Evaluation of Brain Activity Using Near-infrared Spectroscopy in Inflammatory Bowel Disease Patients
title_short	Evaluation of Brain Activity Using Near-infrared Spectroscopy in Inflammatory Bowel Disease Patients
title_full	Evaluation of Brain Activity Using Near-infrared Spectroscopy in Inflammatory Bowel Disease Patients
title_fullStr	Evaluation of Brain Activity Using Near-infrared Spectroscopy in Inflammatory Bowel Disease Patients
title_full_unstemmed	Evaluation of Brain Activity Using Near-infrared Spectroscopy in Inflammatory Bowel Disease Patients
title_sort	evaluation of brain activity using near-infrared spectroscopy in inflammatory bowel disease patients
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/a51cf175a8914196a14f71f32c3bfd0f
work_keys_str_mv	AT tatsuofujiwara evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients AT soichikono evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients AT kyokokatakura evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients AT kazumichiabe evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients AT atsushitakahashi evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients AT naohikogunji evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients AT akiyokokawa evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients AT kazumasakawashima evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients AT riekosuzuki evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients AT akirawada evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients AT itarumiura evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients AT hirookiyabe evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients AT hiromasaohira evaluationofbrainactivityusingnearinfraredspectroscopyininflammatoryboweldiseasepatients
_version_	1718387956314537984

Evaluation of Brain Activity Using Near-infrared Spectroscopy in Inflammatory Bowel Disease Patients

Ejemplares similares