Molecular insights into the interaction between Plasmodium falciparum apical membrane antigen 1 and an invasion-inhibitory peptide.

Apical membrane antigen 1 (AMA1) of the human malaria parasite Plasmodium falciparum has been implicated in invasion of the host erythrocyte. It interacts with malarial rhoptry neck (RON) proteins in the moving junction that forms between the host cell and the invading parasite. Agents that block th...

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Autores principales: Geqing Wang, Christopher A MacRaild, Biswaranjan Mohanty, Mehdi Mobli, Nathan P Cowieson, Robin F Anders, Jamie S Simpson, Sheena McGowan, Raymond S Norton, Martin J Scanlon
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/a51fd55313c34feba2785836de28f0c3
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