Targeted inactivation of dipeptidyl peptidase 9 enzymatic activity causes mouse neonate lethality.

Dipeptidyl Peptidase (DPP) 4 and related dipeptidyl peptidases are emerging as current and potential therapeutic targets. DPP9 is an intracellular protease that is regulated by redox status and by SUMO1. DPP9 can influence antigen processing, epidermal growth factor (EGF)-mediated signaling and tumo...

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Main Authors: Margaret G Gall, Yiqian Chen, Ana Julia Vieira de Ribeiro, Hui Zhang, Charles G Bailey, Derek S Spielman, Denise M T Yu, Mark D Gorrell
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/a53568362b3e4e698b1e39e9eef2c700
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