A novel role for pro-coagulant microvesicles in the early host defense against streptococcus pyogenes.

Previous studies have shown that stimulation of whole blood or peripheral blood mononuclear cells with bacterial virulence factors results in the sequestration of pro-coagulant microvesicles (MVs). These particles explore their clotting activity via the extrinsic and intrinsic pathway of coagulation...

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Bibliographic Details
Main Authors: Sonja Oehmcke, Johannes Westman, Johan Malmström, Matthias Mörgelin, Anders I Olin, Bernd Kreikemeyer, Heiko Herwald
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
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Online Access:https://doaj.org/article/a5357a4d02c94a959fb8eb244dbf2723
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