Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection

Caenorhabditis elegans exhibits multigenerational adaptation to bacterial infection but the mechanisms remain unclear. Here, the authors show that C. elegans parental exposure to Pseudomonas vranovensis promotes offspring resistance to infection, a process mediated by the cysteine synthases CYSL-1 a...

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Autores principales: Nicholas O. Burton, Cristian Riccio, Alexandra Dallaire, Jonathan Price, Benjamin Jenkins, Albert Koulman, Eric A. Miska
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a53cdf9743ff4aab84938b0cc37d4ee8
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spelling oai:doaj.org-article:a53cdf9743ff4aab84938b0cc37d4ee82021-12-02T14:40:40ZCysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection10.1038/s41467-020-15555-82041-1723https://doaj.org/article/a53cdf9743ff4aab84938b0cc37d4ee82020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15555-8https://doaj.org/toc/2041-1723Caenorhabditis elegans exhibits multigenerational adaptation to bacterial infection but the mechanisms remain unclear. Here, the authors show that C. elegans parental exposure to Pseudomonas vranovensis promotes offspring resistance to infection, a process mediated by the cysteine synthases CYSL-1 and CYSL-2.Nicholas O. BurtonCristian RiccioAlexandra DallaireJonathan PriceBenjamin JenkinsAlbert KoulmanEric A. MiskaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nicholas O. Burton
Cristian Riccio
Alexandra Dallaire
Jonathan Price
Benjamin Jenkins
Albert Koulman
Eric A. Miska
Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection
description Caenorhabditis elegans exhibits multigenerational adaptation to bacterial infection but the mechanisms remain unclear. Here, the authors show that C. elegans parental exposure to Pseudomonas vranovensis promotes offspring resistance to infection, a process mediated by the cysteine synthases CYSL-1 and CYSL-2.
format article
author Nicholas O. Burton
Cristian Riccio
Alexandra Dallaire
Jonathan Price
Benjamin Jenkins
Albert Koulman
Eric A. Miska
author_facet Nicholas O. Burton
Cristian Riccio
Alexandra Dallaire
Jonathan Price
Benjamin Jenkins
Albert Koulman
Eric A. Miska
author_sort Nicholas O. Burton
title Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection
title_short Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection
title_full Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection
title_fullStr Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection
title_full_unstemmed Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection
title_sort cysteine synthases cysl-1 and cysl-2 mediate c. elegans heritable adaptation to p. vranovensis infection
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/a53cdf9743ff4aab84938b0cc37d4ee8
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