A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer [version 2; peer review: 1 approved, 3 approved with reservations]

Automated patch-clamp platforms are widely used and vital tools in both academia and industry to enable high-throughput studies such as drug screening. A leak current to ground occurs whenever the seal between a pipette and cell (or internal solution and cell in high-throughput machines) is not perf...

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Autores principales: Chon Lok Lei, Alan Fabbri, Dominic G. Whittaker, Michael Clerx, Monique J. Windley, Adam P. Hill, Gary R. Mirams, Teun P. de Boer
Formato: article
Lenguaje:EN
Publicado: Wellcome 2021
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Acceso en línea:https://doaj.org/article/a53e5521451443e3b5ff249890662cc0
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