Risk Factors of Coexisting Septic Spondylitis and Arthritis: A Case-Control Study in a Tertiary Referral Hospital

Introduction: In patients under immunosuppression or severe sepsis, it is sometimes manifested as coexisting septic arthritis and spondylitis. The aim of this study is to evaluate and investigate the risk factors of infectious spondylitis associated with septic arthritis. Methods: The study retrospe...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sheng-Fen Wang, Po-Liang Lai, Hsiang-Fu Liu, Tsung-Ting Tsai, Yu-Chih Lin, Yun-Da Li, Ping-Yeh Chiu, Ming-Kai Hsieh, Fu-Cheng Kao
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	infectious spondylitis septic arthritis hypoalbuminemia psoas abscess Medicine R
Acceso en línea:	https://doaj.org/article/a53f5b422f0c40688540803f88467dcc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a53f5b422f0c40688540803f88467dcc
record_format	dspace
spelling	oai:doaj.org-article:a53f5b422f0c40688540803f88467dcc2021-11-25T18:01:55ZRisk Factors of Coexisting Septic Spondylitis and Arthritis: A Case-Control Study in a Tertiary Referral Hospital10.3390/jcm102253452077-0383https://doaj.org/article/a53f5b422f0c40688540803f88467dcc2021-11-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/22/5345https://doaj.org/toc/2077-0383Introduction: In patients under immunosuppression or severe sepsis, it is sometimes manifested as coexisting septic arthritis and spondylitis. The aim of this study is to evaluate and investigate the risk factors of infectious spondylitis associated with septic arthritis. Methods: The study retrospectively reviewed the patients diagnosed with infectious spondylitis between January 2010 and September 2018 for risk factors of coexisting major joint septic arthritis. Results: A total of 10 patients with infectious spondylitis and coexisting septic arthritis comprised the study group. Fifty matched patients with solely infectious spondylitis were selected as the control group. Major risk factors include preoperative C-reactive protein (<i>p</i> = 0.001), hypoalbuminemia (<i>p</i> = 0.011), history of total joint replacement (<i>p</i> < 0.001), duration of preoperative antibiotics treatment (<i>p</i> = 0.038) and psoas muscle abscess (<i>p</i> < 0.001). Conclusion: Infectious spondylitis and septic arthritis are thought of as medical emergencies due to their high mortality and morbidity. Our study evaluated 5 risk factors as significant major findings: hypoalbuminemia (<3.4 g/dL), higher preoperative CRP (>130 mg/L), psoas muscle abscess, longer preoperative antibiotics treatment (>8 days) and history of total joint replacement. Clinicians should pay attention to the patients with those five factors to detect the coexisting infections as early as possible.Sheng-Fen WangPo-Liang LaiHsiang-Fu LiuTsung-Ting TsaiYu-Chih LinYun-Da LiPing-Yeh ChiuMing-Kai HsiehFu-Cheng KaoMDPI AGarticleinfectious spondylitisseptic arthritishypoalbuminemiapsoas abscessMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5345, p 5345 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	infectious spondylitis septic arthritis hypoalbuminemia psoas abscess Medicine R
spellingShingle	infectious spondylitis septic arthritis hypoalbuminemia psoas abscess Medicine R Sheng-Fen Wang Po-Liang Lai Hsiang-Fu Liu Tsung-Ting Tsai Yu-Chih Lin Yun-Da Li Ping-Yeh Chiu Ming-Kai Hsieh Fu-Cheng Kao Risk Factors of Coexisting Septic Spondylitis and Arthritis: A Case-Control Study in a Tertiary Referral Hospital
description	Introduction: In patients under immunosuppression or severe sepsis, it is sometimes manifested as coexisting septic arthritis and spondylitis. The aim of this study is to evaluate and investigate the risk factors of infectious spondylitis associated with septic arthritis. Methods: The study retrospectively reviewed the patients diagnosed with infectious spondylitis between January 2010 and September 2018 for risk factors of coexisting major joint septic arthritis. Results: A total of 10 patients with infectious spondylitis and coexisting septic arthritis comprised the study group. Fifty matched patients with solely infectious spondylitis were selected as the control group. Major risk factors include preoperative C-reactive protein (<i>p</i> = 0.001), hypoalbuminemia (<i>p</i> = 0.011), history of total joint replacement (<i>p</i> < 0.001), duration of preoperative antibiotics treatment (<i>p</i> = 0.038) and psoas muscle abscess (<i>p</i> < 0.001). Conclusion: Infectious spondylitis and septic arthritis are thought of as medical emergencies due to their high mortality and morbidity. Our study evaluated 5 risk factors as significant major findings: hypoalbuminemia (<3.4 g/dL), higher preoperative CRP (>130 mg/L), psoas muscle abscess, longer preoperative antibiotics treatment (>8 days) and history of total joint replacement. Clinicians should pay attention to the patients with those five factors to detect the coexisting infections as early as possible.
format	article
author	Sheng-Fen Wang Po-Liang Lai Hsiang-Fu Liu Tsung-Ting Tsai Yu-Chih Lin Yun-Da Li Ping-Yeh Chiu Ming-Kai Hsieh Fu-Cheng Kao
author_facet	Sheng-Fen Wang Po-Liang Lai Hsiang-Fu Liu Tsung-Ting Tsai Yu-Chih Lin Yun-Da Li Ping-Yeh Chiu Ming-Kai Hsieh Fu-Cheng Kao
author_sort	Sheng-Fen Wang
title	Risk Factors of Coexisting Septic Spondylitis and Arthritis: A Case-Control Study in a Tertiary Referral Hospital
title_short	Risk Factors of Coexisting Septic Spondylitis and Arthritis: A Case-Control Study in a Tertiary Referral Hospital
title_full	Risk Factors of Coexisting Septic Spondylitis and Arthritis: A Case-Control Study in a Tertiary Referral Hospital
title_fullStr	Risk Factors of Coexisting Septic Spondylitis and Arthritis: A Case-Control Study in a Tertiary Referral Hospital
title_full_unstemmed	Risk Factors of Coexisting Septic Spondylitis and Arthritis: A Case-Control Study in a Tertiary Referral Hospital
title_sort	risk factors of coexisting septic spondylitis and arthritis: a case-control study in a tertiary referral hospital
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/a53f5b422f0c40688540803f88467dcc
work_keys_str_mv	AT shengfenwang riskfactorsofcoexistingsepticspondylitisandarthritisacasecontrolstudyinatertiaryreferralhospital AT polianglai riskfactorsofcoexistingsepticspondylitisandarthritisacasecontrolstudyinatertiaryreferralhospital AT hsiangfuliu riskfactorsofcoexistingsepticspondylitisandarthritisacasecontrolstudyinatertiaryreferralhospital AT tsungtingtsai riskfactorsofcoexistingsepticspondylitisandarthritisacasecontrolstudyinatertiaryreferralhospital AT yuchihlin riskfactorsofcoexistingsepticspondylitisandarthritisacasecontrolstudyinatertiaryreferralhospital AT yundali riskfactorsofcoexistingsepticspondylitisandarthritisacasecontrolstudyinatertiaryreferralhospital AT pingyehchiu riskfactorsofcoexistingsepticspondylitisandarthritisacasecontrolstudyinatertiaryreferralhospital AT mingkaihsieh riskfactorsofcoexistingsepticspondylitisandarthritisacasecontrolstudyinatertiaryreferralhospital AT fuchengkao riskfactorsofcoexistingsepticspondylitisandarthritisacasecontrolstudyinatertiaryreferralhospital
_version_	1718411697632313344

Risk Factors of Coexisting Septic Spondylitis and Arthritis: A Case-Control Study in a Tertiary Referral Hospital

Ejemplares similares