A histone methyltransferase modulates antigenic variation in African trypanosomes.

To evade the host immune system, several pathogens periodically change their cell-surface epitopes. In the African trypanosomes, antigenic variation is achieved by tightly regulating the expression of a multigene family encoding a large repertoire of variant surface glycoproteins (VSGs). Immune evas...

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Auteurs principaux: Luisa M Figueiredo, Christian J Janzen, George A M Cross
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2008
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Accès en ligne:https://doaj.org/article/a54360074b6e4c978542bf8e10e3199a
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