Genome-wide analysis of copy number variation identifies candidate gene loci associated with the progression of non-alcoholic fatty liver disease.

Genome-wide analysis of copy number variation identifies candidate gene loci associated with the progression of non-alcoholic fatty liver disease.

Between 10 and 25% of individuals with non-alcoholic fatty liver disease (NAFLD) develop hepatic fibrosis leading to cirrhosis and hepatocellular carcinoma (HCC). To investigate the molecular basis of disease progression, we performed a genome-wide analysis of copy number variation (CNV) in a total...

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Autores principales: Shamsul Mohd Zain, Rosmawati Mohamed, David N Cooper, Rozaimi Razali, Sanjay Rampal, Sanjiv Mahadeva, Wah-Kheong Chan, Arif Anwar, Nurul Shielawati Mohamed Rosli, Anis Shafina Mahfudz, Phaik-Leng Cheah, Roma Choudhury Basu, Zahurin Mohamed
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a543aa02099c4469afb9733498d5a2f0
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