Deoxyfluorination of alcohols with 3,3-difluoro-1,2-diarylcyclopropenes

Fluorination of organic molecules can dramatically change the properties and is commonly used for the synthesis of bioactive molecules. Here, the authors report the deoxyfluorination of alcohols and the selective monofluorination of diols using bench stable, tunable difluorocyclopropene reagents.

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Autores principales: Lingchun Li, Chuanfa Ni, Fei Wang, Jinbo Hu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/a543bfff6b39429489f2280db98b4d64
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spelling oai:doaj.org-article:a543bfff6b39429489f2280db98b4d642021-12-02T15:35:26ZDeoxyfluorination of alcohols with 3,3-difluoro-1,2-diarylcyclopropenes10.1038/ncomms133202041-1723https://doaj.org/article/a543bfff6b39429489f2280db98b4d642016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13320https://doaj.org/toc/2041-1723Fluorination of organic molecules can dramatically change the properties and is commonly used for the synthesis of bioactive molecules. Here, the authors report the deoxyfluorination of alcohols and the selective monofluorination of diols using bench stable, tunable difluorocyclopropene reagents.Lingchun LiChuanfa NiFei WangJinbo HuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lingchun Li
Chuanfa Ni
Fei Wang
Jinbo Hu
Deoxyfluorination of alcohols with 3,3-difluoro-1,2-diarylcyclopropenes
description Fluorination of organic molecules can dramatically change the properties and is commonly used for the synthesis of bioactive molecules. Here, the authors report the deoxyfluorination of alcohols and the selective monofluorination of diols using bench stable, tunable difluorocyclopropene reagents.
format article
author Lingchun Li
Chuanfa Ni
Fei Wang
Jinbo Hu
author_facet Lingchun Li
Chuanfa Ni
Fei Wang
Jinbo Hu
author_sort Lingchun Li
title Deoxyfluorination of alcohols with 3,3-difluoro-1,2-diarylcyclopropenes
title_short Deoxyfluorination of alcohols with 3,3-difluoro-1,2-diarylcyclopropenes
title_full Deoxyfluorination of alcohols with 3,3-difluoro-1,2-diarylcyclopropenes
title_fullStr Deoxyfluorination of alcohols with 3,3-difluoro-1,2-diarylcyclopropenes
title_full_unstemmed Deoxyfluorination of alcohols with 3,3-difluoro-1,2-diarylcyclopropenes
title_sort deoxyfluorination of alcohols with 3,3-difluoro-1,2-diarylcyclopropenes
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/a543bfff6b39429489f2280db98b4d64
work_keys_str_mv AT lingchunli deoxyfluorinationofalcoholswith33difluoro12diarylcyclopropenes
AT chuanfani deoxyfluorinationofalcoholswith33difluoro12diarylcyclopropenes
AT feiwang deoxyfluorinationofalcoholswith33difluoro12diarylcyclopropenes
AT jinbohu deoxyfluorinationofalcoholswith33difluoro12diarylcyclopropenes
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