Thymoquinone nanoparticles protect against cisplatin-induced nephrotoxicity in Ehrlich carcinoma model without compromising cisplatin anti-cancer efficacy

Thymoquinone nanoparticles protect against cisplatin-induced nephrotoxicity in Ehrlich carcinoma model without compromising cisplatin anti-cancer efficacy

Objectives: Cisplatin (CISP) is an effective chemotherapy used in the treatment of various types of cancer, but it causes nephrotoxicity and other adverse effects. Thymoquinone (THY) is an effective anti-inflammatory and antioxidant compound, which might protects against many chemotherapies associat...

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Bibliographic Details
Main Authors: Steve Harkaeh, Yousef Qari, Hanaa Tashkandi, Mohammed Almuhayawi, Saber H. Saber, Emad aljahdali, Nagla El-Shitany, Soad Shaker, Filipa Lucas, Turki Alamri, Soad Al-Jaouni, Shaker Mousa
Format: article
Language:EN
Published: Elsevier 2022
Subjects:
Cisplatin
Thymoquinone
Nephrotoxicity
Ehrlich
Antioxidant
Anti-inflammatory
Science (General)
Q1-390
Online Access:https://doaj.org/article/a544168d522d4889b4e1b833fc72f442
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https://doaj.org/article/a544168d522d4889b4e1b833fc72f442

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