Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways

Animals can adapt their body size to changing environments (e.g., temperature) but the underlying molecular mechanisms are unknown. Here, the authors show that temperature and the genetic factors insulin-like peptide receptor and FoxO determine size in Hydra via the conserved pathways (Wnt/TGF-β).

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Autores principales: Benedikt M. Mortzfeld, Jan Taubenheim, Alexander V. Klimovich, Sebastian Fraune, Philip Rosenstiel, Thomas C. G. Bosch
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/a54475c745684a26b3831a7fe24847f4
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