The role of phospholipase D in modulating the MTOR signaling pathway in polycystic kidney disease.

The role of phospholipase D in modulating the MTOR signaling pathway in polycystic kidney disease.

The mammalian target of rapamycin (mTOR) signaling pathway is aberrantly activated in polycystic kidney disease (PKD). Emerging evidence suggests that phospholipase D (PLD) and its product phosphatidic acid (PA) regulate mTOR activity. In this study, we assessed in vitro the regulatory function of P...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yang Liu, Andres Käch, Urs Ziegler, Albert C M Ong, Darren P Wallace, Alexandre Arcaro, Andreas L Serra
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a546f237ed6a4c50ac5fabc86144f933
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares