Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments

Abstract Recurrent complex spinal tuberculosis accompanied by sinus tract formation is one of the most common and complex types of recurrent tuberculosis. To date, only very few studies have reported the strategies and effectiveness of surgical treatments on postoperative recurrent spinal tuberculos...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Biao Wang, Lingbo Kong, Ziqi Zhu, Wenjie Gao, Hua Guo, Xiaodong Wang, Hui Li, Qinpeng Zhao, Haiping Zhang, Dingjun Hao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a5472fed54e84bbe89176c1c07564c64
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a5472fed54e84bbe89176c1c07564c64
record_format	dspace
spelling	oai:doaj.org-article:a5472fed54e84bbe89176c1c07564c642021-12-02T16:07:50ZRecurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments10.1038/s41598-018-25142-z2045-2322https://doaj.org/article/a5472fed54e84bbe89176c1c07564c642018-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-25142-zhttps://doaj.org/toc/2045-2322Abstract Recurrent complex spinal tuberculosis accompanied by sinus tract formation is one of the most common and complex types of recurrent tuberculosis. To date, only very few studies have reported the strategies and effectiveness of surgical treatments on postoperative recurrent spinal tuberculosis accompanied by sinus tract formation. In this study, 21 recurrent patients out of 87 patients with complex spinal tuberculosis were reviewed. The data of the patients, including age, gender, existence of drug-resistant mycobacterium tuberculosis, postoperative standard chemotherapy, completeness of lesion debridement, reconstruction of the spinal stability, nutritional status, accompaniment by tuberculosis in other regions, timing of the operations, and areas of the lesions, were collected for single- and multiple-factor analyses. The clinical outcomes were evaluated by long-term follow-ups. The results showed that 7 factors were significantly associated with postoperative recurrence of complex spinal tuberculosis accompanied by sinus tract formation. This suggested that when we treat complex spinal tuberculosis, we should pay more attention to these seven indicators to avoid postoperative recurrence, and our clinical outcomes suggested that it is difficult to treat recurrent complicated spinal tuberculosis combined with sinus tract formation. The key for successful surgical treatment includes effective chemotherapy, radical debridement and proper reconstruction of spinal stability.Biao WangLingbo KongZiqi ZhuWenjie GaoHua GuoXiaodong WangHui LiQinpeng ZhaoHaiping ZhangDingjun HaoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Biao Wang Lingbo Kong Ziqi Zhu Wenjie Gao Hua Guo Xiaodong Wang Hui Li Qinpeng Zhao Haiping Zhang Dingjun Hao Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
description	Abstract Recurrent complex spinal tuberculosis accompanied by sinus tract formation is one of the most common and complex types of recurrent tuberculosis. To date, only very few studies have reported the strategies and effectiveness of surgical treatments on postoperative recurrent spinal tuberculosis accompanied by sinus tract formation. In this study, 21 recurrent patients out of 87 patients with complex spinal tuberculosis were reviewed. The data of the patients, including age, gender, existence of drug-resistant mycobacterium tuberculosis, postoperative standard chemotherapy, completeness of lesion debridement, reconstruction of the spinal stability, nutritional status, accompaniment by tuberculosis in other regions, timing of the operations, and areas of the lesions, were collected for single- and multiple-factor analyses. The clinical outcomes were evaluated by long-term follow-ups. The results showed that 7 factors were significantly associated with postoperative recurrence of complex spinal tuberculosis accompanied by sinus tract formation. This suggested that when we treat complex spinal tuberculosis, we should pay more attention to these seven indicators to avoid postoperative recurrence, and our clinical outcomes suggested that it is difficult to treat recurrent complicated spinal tuberculosis combined with sinus tract formation. The key for successful surgical treatment includes effective chemotherapy, radical debridement and proper reconstruction of spinal stability.
format	article
author	Biao Wang Lingbo Kong Ziqi Zhu Wenjie Gao Hua Guo Xiaodong Wang Hui Li Qinpeng Zhao Haiping Zhang Dingjun Hao
author_facet	Biao Wang Lingbo Kong Ziqi Zhu Wenjie Gao Hua Guo Xiaodong Wang Hui Li Qinpeng Zhao Haiping Zhang Dingjun Hao
author_sort	Biao Wang
title	Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
title_short	Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
title_full	Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
title_fullStr	Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
title_full_unstemmed	Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
title_sort	recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/a5472fed54e84bbe89176c1c07564c64
work_keys_str_mv	AT biaowang recurrentcomplexspinaltuberculosisaccompaniedbysinustractformationcausesofrecurrenceandclinicaltreatments AT lingbokong recurrentcomplexspinaltuberculosisaccompaniedbysinustractformationcausesofrecurrenceandclinicaltreatments AT ziqizhu recurrentcomplexspinaltuberculosisaccompaniedbysinustractformationcausesofrecurrenceandclinicaltreatments AT wenjiegao recurrentcomplexspinaltuberculosisaccompaniedbysinustractformationcausesofrecurrenceandclinicaltreatments AT huaguo recurrentcomplexspinaltuberculosisaccompaniedbysinustractformationcausesofrecurrenceandclinicaltreatments AT xiaodongwang recurrentcomplexspinaltuberculosisaccompaniedbysinustractformationcausesofrecurrenceandclinicaltreatments AT huili recurrentcomplexspinaltuberculosisaccompaniedbysinustractformationcausesofrecurrenceandclinicaltreatments AT qinpengzhao recurrentcomplexspinaltuberculosisaccompaniedbysinustractformationcausesofrecurrenceandclinicaltreatments AT haipingzhang recurrentcomplexspinaltuberculosisaccompaniedbysinustractformationcausesofrecurrenceandclinicaltreatments AT dingjunhao recurrentcomplexspinaltuberculosisaccompaniedbysinustractformationcausesofrecurrenceandclinicaltreatments
_version_	1718384735074385920

Recurrent complex spinal tuberculosis accompanied by sinus tract formation: causes of recurrence and clinical treatments

Ejemplares similares