Caspase-1 and IL-1β processing in a teleost fish.

Interleukine-1β (IL-1β) is the most studied pro-inflammatory cytokine, playing a central role in the generation of systemic and local responses to infection, injury, and immunological challenges. In mammals, IL-1β is synthesized as an inactive 31 kDa precursor that is cleaved by caspase-1 generating...

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Auteurs principaux: Marta I R Reis, Ana do Vale, Pedro J B Pereira, Jorge E Azevedo, Nuno M S Dos Santos
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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R
Q
Accès en ligne:https://doaj.org/article/a54b338533c143e7b7aa3d0d767b8813
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