Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas
Radiation-induced meningiomas are often more aggressive than sporadic ones. In this study, the authors perform an exome, methylation and RNA-seq analysis of 31 cases of radiation-induced meningioma and show NF2 rearrangement, an observation previously unreported in the sporadic tumors.
Guardado en:
Autores principales: | Sameer Agnihotri, Suganth Suppiah, Peter D. Tonge, Shahrzad Jalali, Arnavaz Danesh, Jeffery P. Bruce, Yasin Mamatjan, George Klironomos, Lior Gonen, Karolyn Au, Sheila Mansouri, Sharin Karimi, Felix Sahm, Andreas von Deimling, Michael D. Taylor, Normand J. Laperriere, Trevor J. Pugh, Kenneth D. Aldape, Gelareh Zadeh |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/a54fecc0556f4be88b38c63cf07148b5 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
CIC protein instability contributes to tumorigenesis in glioblastoma
por: Severa Bunda, et al.
Publicado: (2019) -
Isolated Intraconal Meningioma
por: Mohammad Taher Rajabi, et al.
Publicado: (2021) -
Intraosseous meningioma mimicking osteosarcoma
por: Ruben Delgado, et al.
Publicado: (2021) -
Peritumoral edema at brain meningiomas
por: V. A. Byvaltsev, et al.
Publicado: (2016) -
Precision histology: how deep learning is poised to revitalize histomorphology for personalized cancer care
por: Ugljesa Djuric, et al.
Publicado: (2017)