Structural and functional analysis of LIM domain-dependent recruitment of paxillin to αvβ3 integrin-positive focal adhesions

Structural and functional analysis of LIM domain-dependent recruitment of paxillin to αvβ3 integrin-positive focal adhesions

Ripamonti et al. provide mechanistic insight into the contribution of individual Paxillin LIM domains in targeting and maintaining the structural integrity of focal adhesions (FAs). They show that mechanical coupling of paxillin in the FA to the plasma membrane or integrin is important for FA stabil...

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Detalles Bibliográficos
Autores principales: Marta Ripamonti, Nicolas Liaudet, Latifeh Azizi, Daniel Bouvard, Vesa P. Hytönen, Bernhard Wehrle-Haller
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/a558e07f6d3d49de97381a3839425b85
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