PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR
PARP1, in addition to its role in DNA repair, has a role in regulating gene transcription via PARylation of target proteins. Here the authors show that HuR is targeted after lipopolysaccharide exposure to regulate the inflammatory gene expression at post-transcriptional level.
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| Autores principales: | , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/a55d7a2a75e7444fa4ab121ed3fd3490 |
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