MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
Abstract. The criteria of reliable validation of population protection against diphtheria on the base of two indices including quantity of antitoxic antibodies to diphtheria and avidity index have been established. For this purposes it was proposed to use the modified variant of ELISA allowed to det...
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Sankt-Peterburg : NIIÈM imeni Pastera
2014
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oai:doaj.org-article:a55f2e90463b4ee08e1527fc270c9ce12021-11-22T07:09:46ZMODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA2220-76192313-739810.15789/2220-7619-2012-4-729-734https://doaj.org/article/a55f2e90463b4ee08e1527fc270c9ce12014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/110https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. The criteria of reliable validation of population protection against diphtheria on the base of two indices including quantity of antitoxic antibodies to diphtheria and avidity index have been established. For this purposes it was proposed to use the modified variant of ELISA allowed to detect both indices simultaneously. The formula of probable development of diphtheria in case of the close contact with patients or Corynebacterium diphtheriae bacteria carriers as well as determination of revaccination time have been proposed. The authors developed “The algorithm of population immunity control and assessment of non-susceptibility to diphtheria” and “The algorithm of micro biological testing of clinical samples for C. diphtheriae”.L. A. KraevaE. A. AlekseevaG. Y. TsenevaL. A. LipatovaG. I. BespalovaSankt-Peterburg : NIIÈM imeni Pasteraarticlediphtheriapost vaccination immunitytoxigenic strainsInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 2, Iss 4, Pp 729-734 (2014) |
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diphtheria post vaccination immunity toxigenic strains Infectious and parasitic diseases RC109-216 |
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diphtheria post vaccination immunity toxigenic strains Infectious and parasitic diseases RC109-216 L. A. Kraeva E. A. Alekseeva G. Y. Tseneva L. A. Lipatova G. I. Bespalova MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA |
description |
Abstract. The criteria of reliable validation of population protection against diphtheria on the base of two indices including quantity of antitoxic antibodies to diphtheria and avidity index have been established. For this purposes it was proposed to use the modified variant of ELISA allowed to detect both indices simultaneously. The formula of probable development of diphtheria in case of the close contact with patients or Corynebacterium diphtheriae bacteria carriers as well as determination of revaccination time have been proposed. The authors developed “The algorithm of population immunity control and assessment of non-susceptibility to diphtheria” and “The algorithm of micro biological testing of clinical samples for C. diphtheriae”. |
format |
article |
author |
L. A. Kraeva E. A. Alekseeva G. Y. Tseneva L. A. Lipatova G. I. Bespalova |
author_facet |
L. A. Kraeva E. A. Alekseeva G. Y. Tseneva L. A. Lipatova G. I. Bespalova |
author_sort |
L. A. Kraeva |
title |
MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA |
title_short |
MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA |
title_full |
MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA |
title_fullStr |
MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA |
title_full_unstemmed |
MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA |
title_sort |
modern approaches in complex laboratory testing for diphtheria |
publisher |
Sankt-Peterburg : NIIÈM imeni Pastera |
publishDate |
2014 |
url |
https://doaj.org/article/a55f2e90463b4ee08e1527fc270c9ce1 |
work_keys_str_mv |
AT lakraeva modernapproachesincomplexlaboratorytestingfordiphtheria AT eaalekseeva modernapproachesincomplexlaboratorytestingfordiphtheria AT gytseneva modernapproachesincomplexlaboratorytestingfordiphtheria AT lalipatova modernapproachesincomplexlaboratorytestingfordiphtheria AT gibespalova modernapproachesincomplexlaboratorytestingfordiphtheria |
_version_ |
1718418059251679232 |