MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA

Abstract. The criteria of reliable validation of population protection against diphtheria on the base of two indices including quantity of antitoxic antibodies to diphtheria and avidity index have been established. For this purposes it was proposed to use the modified variant of ELISA allowed to det...

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Autores principales: L. A. Kraeva, E. A. Alekseeva, G. Y. Tseneva, L. A. Lipatova, G. I. Bespalova
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Lenguaje:RU
Publicado: Sankt-Peterburg : NIIÈM imeni Pastera 2014
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Acceso en línea:https://doaj.org/article/a55f2e90463b4ee08e1527fc270c9ce1
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spelling oai:doaj.org-article:a55f2e90463b4ee08e1527fc270c9ce12021-11-22T07:09:46ZMODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA2220-76192313-739810.15789/2220-7619-2012-4-729-734https://doaj.org/article/a55f2e90463b4ee08e1527fc270c9ce12014-07-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/110https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Abstract. The criteria of reliable validation of population protection against diphtheria on the base of two indices including quantity of antitoxic antibodies to diphtheria and avidity index have been established. For this purposes it was proposed to use the modified variant of ELISA allowed to detect both indices simultaneously. The formula of probable development of diphtheria in case of the close contact with patients or Corynebacterium diphtheriae bacteria carriers as well as determination of revaccination time have been proposed. The authors developed “The algorithm of population immunity control and assessment of non-susceptibility to diphtheria” and “The algorithm of micro biological testing of clinical samples for C. diphtheriae”.L. A. KraevaE. A. AlekseevaG. Y. TsenevaL. A. LipatovaG. I. BespalovaSankt-Peterburg : NIIÈM imeni Pasteraarticlediphtheriapost vaccination immunitytoxigenic strainsInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 2, Iss 4, Pp 729-734 (2014)
institution DOAJ
collection DOAJ
language RU
topic diphtheria
post vaccination immunity
toxigenic strains
Infectious and parasitic diseases
RC109-216
spellingShingle diphtheria
post vaccination immunity
toxigenic strains
Infectious and parasitic diseases
RC109-216
L. A. Kraeva
E. A. Alekseeva
G. Y. Tseneva
L. A. Lipatova
G. I. Bespalova
MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
description Abstract. The criteria of reliable validation of population protection against diphtheria on the base of two indices including quantity of antitoxic antibodies to diphtheria and avidity index have been established. For this purposes it was proposed to use the modified variant of ELISA allowed to detect both indices simultaneously. The formula of probable development of diphtheria in case of the close contact with patients or Corynebacterium diphtheriae bacteria carriers as well as determination of revaccination time have been proposed. The authors developed “The algorithm of population immunity control and assessment of non-susceptibility to diphtheria” and “The algorithm of micro biological testing of clinical samples for C. diphtheriae”.
format article
author L. A. Kraeva
E. A. Alekseeva
G. Y. Tseneva
L. A. Lipatova
G. I. Bespalova
author_facet L. A. Kraeva
E. A. Alekseeva
G. Y. Tseneva
L. A. Lipatova
G. I. Bespalova
author_sort L. A. Kraeva
title MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
title_short MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
title_full MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
title_fullStr MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
title_full_unstemmed MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA
title_sort modern approaches in complex laboratory testing for diphtheria
publisher Sankt-Peterburg : NIIÈM imeni Pastera
publishDate 2014
url https://doaj.org/article/a55f2e90463b4ee08e1527fc270c9ce1
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AT gytseneva modernapproachesincomplexlaboratorytestingfordiphtheria
AT lalipatova modernapproachesincomplexlaboratorytestingfordiphtheria
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