Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG)
Farhad Salehzadeh,1 Yusef Mohammadikebar,2 Afsaneh Enteshary,2 Omid Ghanbarpour,1 Mehrdad Mirzarahimi11Department of Pediatric, Bouali Children’s Hospital, Ardabil University of Medical Sciences (ARUMS), Ardabil, Iran; 2Department of Internal Medicine, Emam Khomeini Hospital, Ardabil Unive...
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Dove Medical Press
2019
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oai:doaj.org-article:a574c8fa76a34d15adc1e8f58986ff1e2021-12-02T05:40:01ZInfliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG)1177-5491https://doaj.org/article/a574c8fa76a34d15adc1e8f58986ff1e2019-05-01T00:00:00Zhttps://www.dovepress.com/infliximab-in-treatment-of-idiopathic-refractory-childhood-pyoderma-ga-peer-reviewed-article-BTThttps://doaj.org/toc/1177-5491Farhad Salehzadeh,1 Yusef Mohammadikebar,2 Afsaneh Enteshary,2 Omid Ghanbarpour,1 Mehrdad Mirzarahimi11Department of Pediatric, Bouali Children’s Hospital, Ardabil University of Medical Sciences (ARUMS), Ardabil, Iran; 2Department of Internal Medicine, Emam Khomeini Hospital, Ardabil University of Medical Sciences (ARUMS), Ardabil, IranAbstract: We report a case of refractory idiopathic childhood pyoderma gangrenosum in a young boy who had suffered from this disease since 3 years of age. He had unfavorable responses and intermittent relapses under different combinations of cytotoxic and steroid therapies. Although there was not much information available about infliximab use for biologic and childhood pyoderma gangrenosum, eventually we decided to use infliximab in this patient. Infliximab showed a dramatic response and resulted in full recovery during 2 years’ follow-up.Keywords: pyoderma gangrenosum, infliximab, childhoodSalehzadeh FMohammadikebar YEnteshary AGhanbarpour OMirzarahimi MDove Medical PressarticlePyoderma GangrenousmInfliximabChildhoodMedicine (General)R5-920ENBiologics: Targets & Therapy, Vol Volume 13, Pp 97-99 (2019) |
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Pyoderma Gangrenousm Infliximab Childhood Medicine (General) R5-920 |
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Pyoderma Gangrenousm Infliximab Childhood Medicine (General) R5-920 Salehzadeh F Mohammadikebar Y Enteshary A Ghanbarpour O Mirzarahimi M Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG) |
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Farhad Salehzadeh,1 Yusef Mohammadikebar,2 Afsaneh Enteshary,2 Omid Ghanbarpour,1 Mehrdad Mirzarahimi11Department of Pediatric, Bouali Children’s Hospital, Ardabil University of Medical Sciences (ARUMS), Ardabil, Iran; 2Department of Internal Medicine, Emam Khomeini Hospital, Ardabil University of Medical Sciences (ARUMS), Ardabil, IranAbstract: We report a case of refractory idiopathic childhood pyoderma gangrenosum in a young boy who had suffered from this disease since 3 years of age. He had unfavorable responses and intermittent relapses under different combinations of cytotoxic and steroid therapies. Although there was not much information available about infliximab use for biologic and childhood pyoderma gangrenosum, eventually we decided to use infliximab in this patient. Infliximab showed a dramatic response and resulted in full recovery during 2 years’ follow-up.Keywords: pyoderma gangrenosum, infliximab, childhood |
format |
article |
author |
Salehzadeh F Mohammadikebar Y Enteshary A Ghanbarpour O Mirzarahimi M |
author_facet |
Salehzadeh F Mohammadikebar Y Enteshary A Ghanbarpour O Mirzarahimi M |
author_sort |
Salehzadeh F |
title |
Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG) |
title_short |
Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG) |
title_full |
Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG) |
title_fullStr |
Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG) |
title_full_unstemmed |
Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG) |
title_sort |
infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (pg) |
publisher |
Dove Medical Press |
publishDate |
2019 |
url |
https://doaj.org/article/a574c8fa76a34d15adc1e8f58986ff1e |
work_keys_str_mv |
AT salehzadehf infliximabintreatmentofidiopathicrefractorychildhoodpyodermagangrenosumpg AT mohammadikebary infliximabintreatmentofidiopathicrefractorychildhoodpyodermagangrenosumpg AT entesharya infliximabintreatmentofidiopathicrefractorychildhoodpyodermagangrenosumpg AT ghanbarpouro infliximabintreatmentofidiopathicrefractorychildhoodpyodermagangrenosumpg AT mirzarahimim infliximabintreatmentofidiopathicrefractorychildhoodpyodermagangrenosumpg |
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1718400313608634368 |