Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG)

Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG)

Farhad Salehzadeh,1 Yusef Mohammadikebar,2 Afsaneh Enteshary,2 Omid Ghanbarpour,1 Mehrdad Mirzarahimi11Department of Pediatric, Bouali Children’s Hospital, Ardabil University of Medical Sciences (ARUMS), Ardabil, Iran; 2Department of Internal Medicine, Emam Khomeini Hospital, Ardabil Unive...

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Autores principales: Salehzadeh F, Mohammadikebar Y, Enteshary A, Ghanbarpour O, Mirzarahimi M
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2019
Materias:
Pyoderma Gangrenousm
Infliximab
Childhood
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/a574c8fa76a34d15adc1e8f58986ff1e
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spelling oai:doaj.org-article:a574c8fa76a34d15adc1e8f58986ff1e2021-12-02T05:40:01ZInfliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG)1177-5491https://doaj.org/article/a574c8fa76a34d15adc1e8f58986ff1e2019-05-01T00:00:00Zhttps://www.dovepress.com/infliximab-in-treatment-of-idiopathic-refractory-childhood-pyoderma-ga-peer-reviewed-article-BTThttps://doaj.org/toc/1177-5491Farhad Salehzadeh,1 Yusef Mohammadikebar,2 Afsaneh Enteshary,2 Omid Ghanbarpour,1 Mehrdad Mirzarahimi11Department of Pediatric, Bouali Children’s Hospital, Ardabil University of Medical Sciences (ARUMS), Ardabil, Iran; 2Department of Internal Medicine, Emam Khomeini Hospital, Ardabil University of Medical Sciences (ARUMS), Ardabil, IranAbstract: We report a case of refractory idiopathic childhood pyoderma gangrenosum in a young boy who had suffered from this disease since 3 years of age. He had unfavorable responses and intermittent relapses under different combinations of cytotoxic and steroid therapies. Although there was not much information available about infliximab use for biologic and childhood pyoderma gangrenosum, eventually we decided to use infliximab in this patient. Infliximab showed a dramatic response and resulted in full recovery during 2 years’ follow-up.Keywords: pyoderma gangrenosum, infliximab, childhoodSalehzadeh FMohammadikebar YEnteshary AGhanbarpour OMirzarahimi MDove Medical PressarticlePyoderma GangrenousmInfliximabChildhoodMedicine (General)R5-920ENBiologics: Targets & Therapy, Vol Volume 13, Pp 97-99 (2019)
institution DOAJ
collection DOAJ
language EN
topic Pyoderma Gangrenousm
Infliximab
Childhood
Medicine (General)
R5-920
spellingShingle Pyoderma Gangrenousm
Infliximab
Childhood
Medicine (General)
R5-920
Salehzadeh F
Mohammadikebar Y
Enteshary A
Ghanbarpour O
Mirzarahimi M
Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG)
description Farhad Salehzadeh,1 Yusef Mohammadikebar,2 Afsaneh Enteshary,2 Omid Ghanbarpour,1 Mehrdad Mirzarahimi11Department of Pediatric, Bouali Children’s Hospital, Ardabil University of Medical Sciences (ARUMS), Ardabil, Iran; 2Department of Internal Medicine, Emam Khomeini Hospital, Ardabil University of Medical Sciences (ARUMS), Ardabil, IranAbstract: We report a case of refractory idiopathic childhood pyoderma gangrenosum in a young boy who had suffered from this disease since 3 years of age. He had unfavorable responses and intermittent relapses under different combinations of cytotoxic and steroid therapies. Although there was not much information available about infliximab use for biologic and childhood pyoderma gangrenosum, eventually we decided to use infliximab in this patient. Infliximab showed a dramatic response and resulted in full recovery during 2 years’ follow-up.Keywords: pyoderma gangrenosum, infliximab, childhood
format article
author Salehzadeh F
Mohammadikebar Y
Enteshary A
Ghanbarpour O
Mirzarahimi M
author_facet Salehzadeh F
Mohammadikebar Y
Enteshary A
Ghanbarpour O
Mirzarahimi M
author_sort Salehzadeh F
title Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG)
title_short Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG)
title_full Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG)
title_fullStr Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG)
title_full_unstemmed Infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (PG)
title_sort infliximab in treatment of idiopathic refractory childhood pyoderma gangrenosum (pg)
publisher Dove Medical Press
publishDate 2019
url https://doaj.org/article/a574c8fa76a34d15adc1e8f58986ff1e
work_keys_str_mv AT salehzadehf infliximabintreatmentofidiopathicrefractorychildhoodpyodermagangrenosumpg
AT mohammadikebary infliximabintreatmentofidiopathicrefractorychildhoodpyodermagangrenosumpg
AT entesharya infliximabintreatmentofidiopathicrefractorychildhoodpyodermagangrenosumpg
AT ghanbarpouro infliximabintreatmentofidiopathicrefractorychildhoodpyodermagangrenosumpg
AT mirzarahimim infliximabintreatmentofidiopathicrefractorychildhoodpyodermagangrenosumpg
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