Aspects of surgical treatment of primary hyperparathyroidism

Aim. To evaluate the results of surgical treatment of patients with primary hyperparathyroidism. Material and methods. The work is based on retrospective and prospective analysis of the results of treatment among 81 patients with typical clinical manifestations of primary hyperparathyroidism in t...

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Autores principales:	R.T. Kuzenko, A.O. Vaсeba, O.S. Gavrylyuk, M.B. Fedorkiv
Formato:	article
Lenguaje:	EN UK
Publicado:	Danylo Halytsky Lviv National Medical University 2019
Materias:	primary hyperparathyroidism, hypercalcemia, operative treatment, parathormone Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/a57c6de01c0a4d169b9b73a6e9eae9df
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spelling	oai:doaj.org-article:a57c6de01c0a4d169b9b73a6e9eae9df2021-11-10T19:49:52ZAspects of surgical treatment of primary hyperparathyroidism1029-42442415-330310.25040/aml2019.01.004https://doaj.org/article/a57c6de01c0a4d169b9b73a6e9eae9df2019-02-01T00:00:00Zhttps://amljournal.com/index.php/journal/article/view/67https://doaj.org/toc/1029-4244https://doaj.org/toc/2415-3303Aim. To evaluate the results of surgical treatment of patients with primary hyperparathyroidism. Material and methods. The work is based on retrospective and prospective analysis of the results of treatment among 81 patients with typical clinical manifestations of primary hyperparathyroidism in the Ivano-Frankivsk Regional Clinical Hospital from 2014 till 2019. As a result of screening, various forms of primary hyperparathyroidism were diagnosed in 49 (60.4%) patients. The removal of one parathyroid gland was performed in 34 (69.3%) patients; of two glandss - in 12 (24.4%) patients. In 3 (6.1%) patients, there was an atypical placement of parathyroid gland;retrotracheal in two cases: and retrosternal in one. Results and discussion.Arenal form of primary hyperparathyroidism was diagnosed in 17 (34.6%) patients;an asymptomatic course - in 14 (28.5%) patients;a mixed form - in 11 (22.4%); a bone form - in 6 (14.2%) . In 2 (4%) patients severe transit hypoparathyroidism developed after the operation. In 7 (63.6%) patients with the mixed form of primary hyperparathyroidism, the pain in the bones and joints reduced significantly after the surgery. Among 6 patients with the bone form of primary hyperparathyroidism after parathyroidectomy, in4 (66.6%) patients endoprosthetics of hip joints was performed due to pathological fractures; a successful osteosynthesis of the femur - in 2 (33.3%) patients. Among 11 (78.5%) patients with asymptomatic form of primary hyperparathyroidism, the values of phosphorous-calcium metabolism were normalized after parathyroidectomy. Thus, only in 3 (6.1%) patients, the level of parathyroid hormone exceeded the normin 2 months after the operation. Conclusions.A diagnosis of primary hyperparathyroidism is an indication for surgical treatment regardless of the form of the disease. Among patients with clinical signs of the disease, in-depth screening allowed diagnosingit in 60.4% of the surveyed.R.T. KuzenkoA.O. VaсebaO.S. GavrylyukM.B. FedorkivDanylo Halytsky Lviv National Medical Universityarticleprimary hyperparathyroidism, hypercalcemia, operative treatment, parathormoneMedicine (General)R5-920ENUKActa Medica Leopoliensia, Vol 25, Iss 1, Pp 4-7 (2019)
institution	DOAJ
collection	DOAJ
language	EN UK
topic	primary hyperparathyroidism, hypercalcemia, operative treatment, parathormone Medicine (General) R5-920
spellingShingle	primary hyperparathyroidism, hypercalcemia, operative treatment, parathormone Medicine (General) R5-920 R.T. Kuzenko A.O. Vaсeba O.S. Gavrylyuk M.B. Fedorkiv Aspects of surgical treatment of primary hyperparathyroidism
description	Aim. To evaluate the results of surgical treatment of patients with primary hyperparathyroidism. Material and methods. The work is based on retrospective and prospective analysis of the results of treatment among 81 patients with typical clinical manifestations of primary hyperparathyroidism in the Ivano-Frankivsk Regional Clinical Hospital from 2014 till 2019. As a result of screening, various forms of primary hyperparathyroidism were diagnosed in 49 (60.4%) patients. The removal of one parathyroid gland was performed in 34 (69.3%) patients; of two glandss - in 12 (24.4%) patients. In 3 (6.1%) patients, there was an atypical placement of parathyroid gland;retrotracheal in two cases: and retrosternal in one. Results and discussion.Arenal form of primary hyperparathyroidism was diagnosed in 17 (34.6%) patients;an asymptomatic course - in 14 (28.5%) patients;a mixed form - in 11 (22.4%); a bone form - in 6 (14.2%) . In 2 (4%) patients severe transit hypoparathyroidism developed after the operation. In 7 (63.6%) patients with the mixed form of primary hyperparathyroidism, the pain in the bones and joints reduced significantly after the surgery. Among 6 patients with the bone form of primary hyperparathyroidism after parathyroidectomy, in4 (66.6%) patients endoprosthetics of hip joints was performed due to pathological fractures; a successful osteosynthesis of the femur - in 2 (33.3%) patients. Among 11 (78.5%) patients with asymptomatic form of primary hyperparathyroidism, the values of phosphorous-calcium metabolism were normalized after parathyroidectomy. Thus, only in 3 (6.1%) patients, the level of parathyroid hormone exceeded the normin 2 months after the operation. Conclusions.A diagnosis of primary hyperparathyroidism is an indication for surgical treatment regardless of the form of the disease. Among patients with clinical signs of the disease, in-depth screening allowed diagnosingit in 60.4% of the surveyed.
format	article
author	R.T. Kuzenko A.O. Vaсeba O.S. Gavrylyuk M.B. Fedorkiv
author_facet	R.T. Kuzenko A.O. Vaсeba O.S. Gavrylyuk M.B. Fedorkiv
author_sort	R.T. Kuzenko
title	Aspects of surgical treatment of primary hyperparathyroidism
title_short	Aspects of surgical treatment of primary hyperparathyroidism
title_full	Aspects of surgical treatment of primary hyperparathyroidism
title_fullStr	Aspects of surgical treatment of primary hyperparathyroidism
title_full_unstemmed	Aspects of surgical treatment of primary hyperparathyroidism
title_sort	aspects of surgical treatment of primary hyperparathyroidism
publisher	Danylo Halytsky Lviv National Medical University
publishDate	2019
url	https://doaj.org/article/a57c6de01c0a4d169b9b73a6e9eae9df
work_keys_str_mv	AT rtkuzenko aspectsofsurgicaltreatmentofprimaryhyperparathyroidism AT aovaseba aspectsofsurgicaltreatmentofprimaryhyperparathyroidism AT osgavrylyuk aspectsofsurgicaltreatmentofprimaryhyperparathyroidism AT mbfedorkiv aspectsofsurgicaltreatmentofprimaryhyperparathyroidism
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Aspects of surgical treatment of primary hyperparathyroidism

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