Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target.
<h4>Background</h4>Trypanosomes can synthesize polyunsaturated fatty acids. Previously, we have shown that they possess stearoyl-CoA desaturase (SCD) and oleate desaturase (OD) to convert stearate (C18) into oleate (C18:1) and linoleate (C18:2), respectively. Here we examine if OD is ess...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2010
|
| Subjects: | |
| Online Access: | https://doaj.org/article/a57c90e94fae4e52835dda6138b4d99d |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|