The negative feedback-loop between the oncomir Mir-24-1 and menin modulates the Men1 tumorigenesis by mimicking the "Knudson's second hit".
Multiple endocrine neoplasia type 1 (MEN1) syndrome is a rare hereditary cancer disorder characterized by tumors of the parathyroids, of the neuroendocrine cells, of the gastro-entero-pancreatic tract, of the anterior pituitary, and by non-endocrine neoplasms and lesions. MEN1 gene, a tumor suppress...
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| Auteurs principaux: | , , , , , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2012
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| Accès en ligne: | https://doaj.org/article/a5975e77b3ec4b5eb9df4ea7a516cb8b |
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