Identification of an enhancer that increases miR-200b~200a~429 gene expression in breast cancer cells.

The miR-200b~200a~429 gene cluster is a key regulator of EMT and cancer metastasis, however the transcription-based mechanisms controlling its expression during this process are not well understood. We have analyzed the miR-200b~200a~429 locus for epigenetic modifications in breast epithelial and me...

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Autores principales:	Joanne L Attema, Andrew G Bert, Yat-Yuen Lim, Natasha Kolesnikoff, David M Lawrence, Katherine A Pillman, Eric Smith, Paul A Drew, Yeesim Khew-Goodall, Frances Shannon, Gregory J Goodall
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a59b1b8a8d0d4780929167d1d70fe099
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Identification of an enhancer that increases miR-200b~200a~429 gene expression in breast cancer cells.

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