B-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling.

B-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling.

Hepatitis C virus (HCV) infection leads to the development of hepatic diseases, as well as extrahepatic disorders such as B-cell non-Hodgkin's lymphoma (B-NHL). To reveal the molecular signalling pathways responsible for HCV-associated B-NHL development, we utilised transgenic (Tg) mice that ex...

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Main Authors: Yuri Kasama, Takuo Mizukami, Hideki Kusunoki, Jan Peveling-Oberhag, Yasumasa Nishito, Makoto Ozawa, Michinori Kohara, Toshiaki Mizuochi, Kyoko Tsukiyama-Kohara
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/a5a0b362ce5b4067af2f69fdf7a1e88a
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https://doaj.org/article/a5a0b362ce5b4067af2f69fdf7a1e88a

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