Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity

Exosomes are RNA-containing lipid vesicles with roles in inter-tissue crosstalk. Here the authors show that exosome release from brown adipocytes is increased upon thermogenic activation, both in vitro and in vivo, and demonstrate that serum levels of exosomal miR-92 reflect brown fat activity in hu...

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Autores principales:	Yong Chen, Joschka J. Buyel, Mark J. W. Hanssen, Franziska Siegel, Ruping Pan, Jennifer Naumann, Michael Schell, Anouk van der Lans, Christian Schlein, Holger Froehlich, Joerg Heeren, Kirsi A. Virtanen, Wouter van Marken Lichtenbelt, Alexander Pfeifer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a5a3002cb6614c3fa06055d50ee9c5fe
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spelling	oai:doaj.org-article:a5a3002cb6614c3fa06055d50ee9c5fe2021-12-02T17:33:07ZExosomal microRNA miR-92a concentration in serum reflects human brown fat activity10.1038/ncomms114202041-1723https://doaj.org/article/a5a3002cb6614c3fa06055d50ee9c5fe2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11420https://doaj.org/toc/2041-1723Exosomes are RNA-containing lipid vesicles with roles in inter-tissue crosstalk. Here the authors show that exosome release from brown adipocytes is increased upon thermogenic activation, both in vitro and in vivo, and demonstrate that serum levels of exosomal miR-92 reflect brown fat activity in humans.Yong ChenJoschka J. BuyelMark J. W. HanssenFranziska SiegelRuping PanJennifer NaumannMichael SchellAnouk van der LansChristian SchleinHolger FroehlichJoerg HeerenKirsi A. VirtanenWouter van Marken LichtenbeltAlexander PfeiferNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yong Chen Joschka J. Buyel Mark J. W. Hanssen Franziska Siegel Ruping Pan Jennifer Naumann Michael Schell Anouk van der Lans Christian Schlein Holger Froehlich Joerg Heeren Kirsi A. Virtanen Wouter van Marken Lichtenbelt Alexander Pfeifer Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity
description	Exosomes are RNA-containing lipid vesicles with roles in inter-tissue crosstalk. Here the authors show that exosome release from brown adipocytes is increased upon thermogenic activation, both in vitro and in vivo, and demonstrate that serum levels of exosomal miR-92 reflect brown fat activity in humans.
format	article
author	Yong Chen Joschka J. Buyel Mark J. W. Hanssen Franziska Siegel Ruping Pan Jennifer Naumann Michael Schell Anouk van der Lans Christian Schlein Holger Froehlich Joerg Heeren Kirsi A. Virtanen Wouter van Marken Lichtenbelt Alexander Pfeifer
author_facet	Yong Chen Joschka J. Buyel Mark J. W. Hanssen Franziska Siegel Ruping Pan Jennifer Naumann Michael Schell Anouk van der Lans Christian Schlein Holger Froehlich Joerg Heeren Kirsi A. Virtanen Wouter van Marken Lichtenbelt Alexander Pfeifer
author_sort	Yong Chen
title	Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity
title_short	Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity
title_full	Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity
title_fullStr	Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity
title_full_unstemmed	Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity
title_sort	exosomal microrna mir-92a concentration in serum reflects human brown fat activity
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/a5a3002cb6614c3fa06055d50ee9c5fe
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Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity

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