Spt6 is a maintenance factor for centromeric CENP-A

CENP-A is a stable centromere mark, although active transcription poses a potential threat for retaining CENP-A through chromatin remodeling and nucleosome eviction. Here, the authors show that maintenance of the centromeric mark is preserved by Spt6, which recycles CENP-A nucleosomes.

Guardado en:

Detalles Bibliográficos
Autores principales:	Georg O. M. Bobkov, Anming Huang, Sebastiaan J. W. van den Berg, Sreyoshi Mitra, Eduard Anselm, Vasiliki Lazou, Sarah Schunter, Regina Feederle, Axel Imhof, Alexandra Lusser, Lars E. T. Jansen, Patrick Heun
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a5a494ec43084ed0a2ef6c3602611b58
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a5a494ec43084ed0a2ef6c3602611b58
record_format	dspace
spelling	oai:doaj.org-article:a5a494ec43084ed0a2ef6c3602611b582021-12-02T17:47:59ZSpt6 is a maintenance factor for centromeric CENP-A10.1038/s41467-020-16695-72041-1723https://doaj.org/article/a5a494ec43084ed0a2ef6c3602611b582020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16695-7https://doaj.org/toc/2041-1723CENP-A is a stable centromere mark, although active transcription poses a potential threat for retaining CENP-A through chromatin remodeling and nucleosome eviction. Here, the authors show that maintenance of the centromeric mark is preserved by Spt6, which recycles CENP-A nucleosomes.Georg O. M. BobkovAnming HuangSebastiaan J. W. van den BergSreyoshi MitraEduard AnselmVasiliki LazouSarah SchunterRegina FeederleAxel ImhofAlexandra LusserLars E. T. JansenPatrick HeunNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Georg O. M. Bobkov Anming Huang Sebastiaan J. W. van den Berg Sreyoshi Mitra Eduard Anselm Vasiliki Lazou Sarah Schunter Regina Feederle Axel Imhof Alexandra Lusser Lars E. T. Jansen Patrick Heun Spt6 is a maintenance factor for centromeric CENP-A
description	CENP-A is a stable centromere mark, although active transcription poses a potential threat for retaining CENP-A through chromatin remodeling and nucleosome eviction. Here, the authors show that maintenance of the centromeric mark is preserved by Spt6, which recycles CENP-A nucleosomes.
format	article
author	Georg O. M. Bobkov Anming Huang Sebastiaan J. W. van den Berg Sreyoshi Mitra Eduard Anselm Vasiliki Lazou Sarah Schunter Regina Feederle Axel Imhof Alexandra Lusser Lars E. T. Jansen Patrick Heun
author_facet	Georg O. M. Bobkov Anming Huang Sebastiaan J. W. van den Berg Sreyoshi Mitra Eduard Anselm Vasiliki Lazou Sarah Schunter Regina Feederle Axel Imhof Alexandra Lusser Lars E. T. Jansen Patrick Heun
author_sort	Georg O. M. Bobkov
title	Spt6 is a maintenance factor for centromeric CENP-A
title_short	Spt6 is a maintenance factor for centromeric CENP-A
title_full	Spt6 is a maintenance factor for centromeric CENP-A
title_fullStr	Spt6 is a maintenance factor for centromeric CENP-A
title_full_unstemmed	Spt6 is a maintenance factor for centromeric CENP-A
title_sort	spt6 is a maintenance factor for centromeric cenp-a
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a5a494ec43084ed0a2ef6c3602611b58
work_keys_str_mv	AT georgombobkov spt6isamaintenancefactorforcentromericcenpa AT anminghuang spt6isamaintenancefactorforcentromericcenpa AT sebastiaanjwvandenberg spt6isamaintenancefactorforcentromericcenpa AT sreyoshimitra spt6isamaintenancefactorforcentromericcenpa AT eduardanselm spt6isamaintenancefactorforcentromericcenpa AT vasilikilazou spt6isamaintenancefactorforcentromericcenpa AT sarahschunter spt6isamaintenancefactorforcentromericcenpa AT reginafeederle spt6isamaintenancefactorforcentromericcenpa AT axelimhof spt6isamaintenancefactorforcentromericcenpa AT alexandralusser spt6isamaintenancefactorforcentromericcenpa AT larsetjansen spt6isamaintenancefactorforcentromericcenpa AT patrickheun spt6isamaintenancefactorforcentromericcenpa
_version_	1718379486399954944

Spt6 is a maintenance factor for centromeric CENP-A

Ejemplares similares