Spt6 is a maintenance factor for centromeric CENP-A

Spt6 is a maintenance factor for centromeric CENP-A

CENP-A is a stable centromere mark, although active transcription poses a potential threat for retaining CENP-A through chromatin remodeling and nucleosome eviction. Here, the authors show that maintenance of the centromeric mark is preserved by Spt6, which recycles CENP-A nucleosomes.

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Detalles Bibliográficos
Autores principales: Georg O. M. Bobkov, Anming Huang, Sebastiaan J. W. van den Berg, Sreyoshi Mitra, Eduard Anselm, Vasiliki Lazou, Sarah Schunter, Regina Feederle, Axel Imhof, Alexandra Lusser, Lars E. T. Jansen, Patrick Heun
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
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Acceso en línea:https://doaj.org/article/a5a494ec43084ed0a2ef6c3602611b58
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