Temporal genetic association and temporal genetic causality methods for dissecting complex networks

Temporal omics data have the potential to dissect complex biological networks. Here the authors develop methods for detecting temporal genetic loci (teQTLs) of quantitative traits monitored over time and inferring causal relationships between traits linked to the locus.

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Autores principales:	Luan Lin, Quan Chen, Jeanne P. Hirsch, Seungyeul Yoo, Kayee Yeung, Roger E. Bumgarner, Zhidong Tu, Eric E. Schadt, Jun Zhu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a5a92736420b413189346af3a37c901d
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spelling	oai:doaj.org-article:a5a92736420b413189346af3a37c901d2021-12-02T16:50:09ZTemporal genetic association and temporal genetic causality methods for dissecting complex networks10.1038/s41467-018-06203-32041-1723https://doaj.org/article/a5a92736420b413189346af3a37c901d2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06203-3https://doaj.org/toc/2041-1723Temporal omics data have the potential to dissect complex biological networks. Here the authors develop methods for detecting temporal genetic loci (teQTLs) of quantitative traits monitored over time and inferring causal relationships between traits linked to the locus.Luan LinQuan ChenJeanne P. HirschSeungyeul YooKayee YeungRoger E. BumgarnerZhidong TuEric E. SchadtJun ZhuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Luan Lin Quan Chen Jeanne P. Hirsch Seungyeul Yoo Kayee Yeung Roger E. Bumgarner Zhidong Tu Eric E. Schadt Jun Zhu Temporal genetic association and temporal genetic causality methods for dissecting complex networks
description	Temporal omics data have the potential to dissect complex biological networks. Here the authors develop methods for detecting temporal genetic loci (teQTLs) of quantitative traits monitored over time and inferring causal relationships between traits linked to the locus.
format	article
author	Luan Lin Quan Chen Jeanne P. Hirsch Seungyeul Yoo Kayee Yeung Roger E. Bumgarner Zhidong Tu Eric E. Schadt Jun Zhu
author_facet	Luan Lin Quan Chen Jeanne P. Hirsch Seungyeul Yoo Kayee Yeung Roger E. Bumgarner Zhidong Tu Eric E. Schadt Jun Zhu
author_sort	Luan Lin
title	Temporal genetic association and temporal genetic causality methods for dissecting complex networks
title_short	Temporal genetic association and temporal genetic causality methods for dissecting complex networks
title_full	Temporal genetic association and temporal genetic causality methods for dissecting complex networks
title_fullStr	Temporal genetic association and temporal genetic causality methods for dissecting complex networks
title_full_unstemmed	Temporal genetic association and temporal genetic causality methods for dissecting complex networks
title_sort	temporal genetic association and temporal genetic causality methods for dissecting complex networks
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/a5a92736420b413189346af3a37c901d
work_keys_str_mv	AT luanlin temporalgeneticassociationandtemporalgeneticcausalitymethodsfordissectingcomplexnetworks AT quanchen temporalgeneticassociationandtemporalgeneticcausalitymethodsfordissectingcomplexnetworks AT jeannephirsch temporalgeneticassociationandtemporalgeneticcausalitymethodsfordissectingcomplexnetworks AT seungyeulyoo temporalgeneticassociationandtemporalgeneticcausalitymethodsfordissectingcomplexnetworks AT kayeeyeung temporalgeneticassociationandtemporalgeneticcausalitymethodsfordissectingcomplexnetworks AT rogerebumgarner temporalgeneticassociationandtemporalgeneticcausalitymethodsfordissectingcomplexnetworks AT zhidongtu temporalgeneticassociationandtemporalgeneticcausalitymethodsfordissectingcomplexnetworks AT ericeschadt temporalgeneticassociationandtemporalgeneticcausalitymethodsfordissectingcomplexnetworks AT junzhu temporalgeneticassociationandtemporalgeneticcausalitymethodsfordissectingcomplexnetworks
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Temporal genetic association and temporal genetic causality methods for dissecting complex networks

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