Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients

The link between chronic obstructive pulmonary disease (COPD) and osteoporosis is unclear and yet to be understood. The study goals were to detect the prevalence of osteoporosis and investigate its predictors among COPD patients. This is a longitudinal study conducted in a tertiary care setting. Dur...

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Autores principales: Ahmad Naoras Bitar, Syed Azhar Syed Sulaiman, Irfhan Ali Bin Hyder Ali, Amer Hayat Khan
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Lenguaje:EN
Publicado: Wolters Kluwer Medknow Publications 2021
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Acceso en línea:https://doaj.org/article/a5b211c78e8b40b796fc0a5a86602dac
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spelling oai:doaj.org-article:a5b211c78e8b40b796fc0a5a86602dac2021-11-12T10:17:53ZPrevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients2231-40400976-209410.4103/japtr.japtr_98_21https://doaj.org/article/a5b211c78e8b40b796fc0a5a86602dac2021-01-01T00:00:00Zhttp://www.japtr.org/article.asp?issn=2231-4040;year=2021;volume=12;issue=4;spage=395;epage=401;aulast=Bitarhttps://doaj.org/toc/2231-4040https://doaj.org/toc/0976-2094The link between chronic obstructive pulmonary disease (COPD) and osteoporosis is unclear and yet to be understood. The study goals were to detect the prevalence of osteoporosis and investigate its predictors among COPD patients. This is a longitudinal study conducted in a tertiary care setting. During the study, patients' bone mineral density was checked, pulmonary parameters were recorded, and a risk assessment tool was validated. Based on T-score, more than 50% of subjects were osteoporotic. Spirometric parameters were significantly lower among osteoporotic patients. For the risk assessment tool, a cutoff point of 34 made the optimum balance between sensitivity and specificity (0.867 and 0.087, respectively) with a generated area under the curve of 0.934. Severe COPD patients were four times at higher risk of getting osteoporosis, forced expiratory volume (FEV) % predicted, and FEV/forced vital capacity was inversely related to the risk of osteoporosis. Patients with severe dyspnea had twice the risk of getting osteoporosis. Osteoporosis was prevalent among COPD patients, and severe COPD patients were at higher risk of getting osteoporosis.Ahmad Naoras BitarSyed Azhar Syed SulaimanIrfhan Ali Bin Hyder AliAmer Hayat KhanWolters Kluwer Medknow Publicationsarticlechronic obstructive pulmonary diseaseosteoporosispredictorsprevalencerisk assessmentTherapeutics. PharmacologyRM1-950Pharmacy and materia medicaRS1-441ENJournal of Advanced Pharmaceutical Technology & Research, Vol 12, Iss 4, Pp 395-401 (2021)
institution DOAJ
collection DOAJ
language EN
topic chronic obstructive pulmonary disease
osteoporosis
predictors
prevalence
risk assessment
Therapeutics. Pharmacology
RM1-950
Pharmacy and materia medica
RS1-441
spellingShingle chronic obstructive pulmonary disease
osteoporosis
predictors
prevalence
risk assessment
Therapeutics. Pharmacology
RM1-950
Pharmacy and materia medica
RS1-441
Ahmad Naoras Bitar
Syed Azhar Syed Sulaiman
Irfhan Ali Bin Hyder Ali
Amer Hayat Khan
Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients
description The link between chronic obstructive pulmonary disease (COPD) and osteoporosis is unclear and yet to be understood. The study goals were to detect the prevalence of osteoporosis and investigate its predictors among COPD patients. This is a longitudinal study conducted in a tertiary care setting. During the study, patients' bone mineral density was checked, pulmonary parameters were recorded, and a risk assessment tool was validated. Based on T-score, more than 50% of subjects were osteoporotic. Spirometric parameters were significantly lower among osteoporotic patients. For the risk assessment tool, a cutoff point of 34 made the optimum balance between sensitivity and specificity (0.867 and 0.087, respectively) with a generated area under the curve of 0.934. Severe COPD patients were four times at higher risk of getting osteoporosis, forced expiratory volume (FEV) % predicted, and FEV/forced vital capacity was inversely related to the risk of osteoporosis. Patients with severe dyspnea had twice the risk of getting osteoporosis. Osteoporosis was prevalent among COPD patients, and severe COPD patients were at higher risk of getting osteoporosis.
format article
author Ahmad Naoras Bitar
Syed Azhar Syed Sulaiman
Irfhan Ali Bin Hyder Ali
Amer Hayat Khan
author_facet Ahmad Naoras Bitar
Syed Azhar Syed Sulaiman
Irfhan Ali Bin Hyder Ali
Amer Hayat Khan
author_sort Ahmad Naoras Bitar
title Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients
title_short Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients
title_full Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients
title_fullStr Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients
title_full_unstemmed Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients
title_sort prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients
publisher Wolters Kluwer Medknow Publications
publishDate 2021
url https://doaj.org/article/a5b211c78e8b40b796fc0a5a86602dac
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AT irfhanalibinhyderali prevalenceriskassessmentandpredictorsofosteoporosisamongchronicobstructivepulmonarydiseasepatients
AT amerhayatkhan prevalenceriskassessmentandpredictorsofosteoporosisamongchronicobstructivepulmonarydiseasepatients
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