Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients
The link between chronic obstructive pulmonary disease (COPD) and osteoporosis is unclear and yet to be understood. The study goals were to detect the prevalence of osteoporosis and investigate its predictors among COPD patients. This is a longitudinal study conducted in a tertiary care setting. Dur...
Guardado en:
Autores principales: | , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Wolters Kluwer Medknow Publications
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/a5b211c78e8b40b796fc0a5a86602dac |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:a5b211c78e8b40b796fc0a5a86602dac |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:a5b211c78e8b40b796fc0a5a86602dac2021-11-12T10:17:53ZPrevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients2231-40400976-209410.4103/japtr.japtr_98_21https://doaj.org/article/a5b211c78e8b40b796fc0a5a86602dac2021-01-01T00:00:00Zhttp://www.japtr.org/article.asp?issn=2231-4040;year=2021;volume=12;issue=4;spage=395;epage=401;aulast=Bitarhttps://doaj.org/toc/2231-4040https://doaj.org/toc/0976-2094The link between chronic obstructive pulmonary disease (COPD) and osteoporosis is unclear and yet to be understood. The study goals were to detect the prevalence of osteoporosis and investigate its predictors among COPD patients. This is a longitudinal study conducted in a tertiary care setting. During the study, patients' bone mineral density was checked, pulmonary parameters were recorded, and a risk assessment tool was validated. Based on T-score, more than 50% of subjects were osteoporotic. Spirometric parameters were significantly lower among osteoporotic patients. For the risk assessment tool, a cutoff point of 34 made the optimum balance between sensitivity and specificity (0.867 and 0.087, respectively) with a generated area under the curve of 0.934. Severe COPD patients were four times at higher risk of getting osteoporosis, forced expiratory volume (FEV) % predicted, and FEV/forced vital capacity was inversely related to the risk of osteoporosis. Patients with severe dyspnea had twice the risk of getting osteoporosis. Osteoporosis was prevalent among COPD patients, and severe COPD patients were at higher risk of getting osteoporosis.Ahmad Naoras BitarSyed Azhar Syed SulaimanIrfhan Ali Bin Hyder AliAmer Hayat KhanWolters Kluwer Medknow Publicationsarticlechronic obstructive pulmonary diseaseosteoporosispredictorsprevalencerisk assessmentTherapeutics. PharmacologyRM1-950Pharmacy and materia medicaRS1-441ENJournal of Advanced Pharmaceutical Technology & Research, Vol 12, Iss 4, Pp 395-401 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
chronic obstructive pulmonary disease osteoporosis predictors prevalence risk assessment Therapeutics. Pharmacology RM1-950 Pharmacy and materia medica RS1-441 |
spellingShingle |
chronic obstructive pulmonary disease osteoporosis predictors prevalence risk assessment Therapeutics. Pharmacology RM1-950 Pharmacy and materia medica RS1-441 Ahmad Naoras Bitar Syed Azhar Syed Sulaiman Irfhan Ali Bin Hyder Ali Amer Hayat Khan Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients |
description |
The link between chronic obstructive pulmonary disease (COPD) and osteoporosis is unclear and yet to be understood. The study goals were to detect the prevalence of osteoporosis and investigate its predictors among COPD patients. This is a longitudinal study conducted in a tertiary care setting. During the study, patients' bone mineral density was checked, pulmonary parameters were recorded, and a risk assessment tool was validated. Based on T-score, more than 50% of subjects were osteoporotic. Spirometric parameters were significantly lower among osteoporotic patients. For the risk assessment tool, a cutoff point of 34 made the optimum balance between sensitivity and specificity (0.867 and 0.087, respectively) with a generated area under the curve of 0.934. Severe COPD patients were four times at higher risk of getting osteoporosis, forced expiratory volume (FEV) % predicted, and FEV/forced vital capacity was inversely related to the risk of osteoporosis. Patients with severe dyspnea had twice the risk of getting osteoporosis. Osteoporosis was prevalent among COPD patients, and severe COPD patients were at higher risk of getting osteoporosis. |
format |
article |
author |
Ahmad Naoras Bitar Syed Azhar Syed Sulaiman Irfhan Ali Bin Hyder Ali Amer Hayat Khan |
author_facet |
Ahmad Naoras Bitar Syed Azhar Syed Sulaiman Irfhan Ali Bin Hyder Ali Amer Hayat Khan |
author_sort |
Ahmad Naoras Bitar |
title |
Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients |
title_short |
Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients |
title_full |
Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients |
title_fullStr |
Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients |
title_full_unstemmed |
Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients |
title_sort |
prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2021 |
url |
https://doaj.org/article/a5b211c78e8b40b796fc0a5a86602dac |
work_keys_str_mv |
AT ahmadnaorasbitar prevalenceriskassessmentandpredictorsofosteoporosisamongchronicobstructivepulmonarydiseasepatients AT syedazharsyedsulaiman prevalenceriskassessmentandpredictorsofosteoporosisamongchronicobstructivepulmonarydiseasepatients AT irfhanalibinhyderali prevalenceriskassessmentandpredictorsofosteoporosisamongchronicobstructivepulmonarydiseasepatients AT amerhayatkhan prevalenceriskassessmentandpredictorsofosteoporosisamongchronicobstructivepulmonarydiseasepatients |
_version_ |
1718431008365215744 |