Spatial disease dynamics of free-living pathogens under pathogen predation

Abstract The epidemiological dynamics of potentially free-living pathogens are often studied with respect to a specific pathogen species (e.g., cholera) and most studies concentrate only on host-pathogen interactions. Here we show that metacommunity-level interactions can alter conventional spatial...

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Autores principales:	Tommi Mononen, Lasse Ruokolainen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a5bcdf33a21349d19913b659b8aca02d
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spelling	oai:doaj.org-article:a5bcdf33a21349d19913b659b8aca02d2021-12-02T11:52:17ZSpatial disease dynamics of free-living pathogens under pathogen predation10.1038/s41598-017-07983-22045-2322https://doaj.org/article/a5bcdf33a21349d19913b659b8aca02d2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07983-2https://doaj.org/toc/2045-2322Abstract The epidemiological dynamics of potentially free-living pathogens are often studied with respect to a specific pathogen species (e.g., cholera) and most studies concentrate only on host-pathogen interactions. Here we show that metacommunity-level interactions can alter conventional spatial disease dynamics. We introduce a pathogen eating consumer species and investigate a deterministic epidemiological model of two habitat patches, where both patches can be occupied by hosts, pathogens, and consumers of free-living pathogens. An isolated habitat patch shows periodic disease outbreaks in the host population, arising from cyclic consumer-pathogen dynamics. On the other hand, consumer dispersal between the patches generate asymmetric disease prevalence, such that the host population in one patch stays disease-free, while disease outbreaks occur in the other patch. Such asymmetry can also arise with host dispersal, where infected hosts carry pathogens to the other patch. This indirect movement of pathogens causes also a counter-intuitive effect: decreasing morbidity in a focal patch under increasing pathogen immigration. Our results underline that community-level interactions influence disease dynamics and consistent spatial asymmetry can arise also in spatially homogeneous systems.Tommi MononenLasse RuokolainenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Tommi Mononen Lasse Ruokolainen Spatial disease dynamics of free-living pathogens under pathogen predation
description	Abstract The epidemiological dynamics of potentially free-living pathogens are often studied with respect to a specific pathogen species (e.g., cholera) and most studies concentrate only on host-pathogen interactions. Here we show that metacommunity-level interactions can alter conventional spatial disease dynamics. We introduce a pathogen eating consumer species and investigate a deterministic epidemiological model of two habitat patches, where both patches can be occupied by hosts, pathogens, and consumers of free-living pathogens. An isolated habitat patch shows periodic disease outbreaks in the host population, arising from cyclic consumer-pathogen dynamics. On the other hand, consumer dispersal between the patches generate asymmetric disease prevalence, such that the host population in one patch stays disease-free, while disease outbreaks occur in the other patch. Such asymmetry can also arise with host dispersal, where infected hosts carry pathogens to the other patch. This indirect movement of pathogens causes also a counter-intuitive effect: decreasing morbidity in a focal patch under increasing pathogen immigration. Our results underline that community-level interactions influence disease dynamics and consistent spatial asymmetry can arise also in spatially homogeneous systems.
format	article
author	Tommi Mononen Lasse Ruokolainen
author_facet	Tommi Mononen Lasse Ruokolainen
author_sort	Tommi Mononen
title	Spatial disease dynamics of free-living pathogens under pathogen predation
title_short	Spatial disease dynamics of free-living pathogens under pathogen predation
title_full	Spatial disease dynamics of free-living pathogens under pathogen predation
title_fullStr	Spatial disease dynamics of free-living pathogens under pathogen predation
title_full_unstemmed	Spatial disease dynamics of free-living pathogens under pathogen predation
title_sort	spatial disease dynamics of free-living pathogens under pathogen predation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/a5bcdf33a21349d19913b659b8aca02d
work_keys_str_mv	AT tommimononen spatialdiseasedynamicsoffreelivingpathogensunderpathogenpredation AT lasseruokolainen spatialdiseasedynamicsoffreelivingpathogensunderpathogenpredation
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Spatial disease dynamics of free-living pathogens under pathogen predation

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