Role of oncogenic KRAS in the prognosis, diagnosis and treatment of colorectal cancer
Abstract Colorectal cancer (CRC) is a heterogeneous disease at the cellular and molecular levels. Kirsten rat sarcoma (KRAS) is a commonly mutated oncogene in CRC, with mutations in approximately 40% of all CRC cases; its mutations result in constitutive activation of the KRAS protein, which acts as...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
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BMC
2021
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| Accès en ligne: | https://doaj.org/article/a5cb9fa2bdcc4009ba782630d37a3d2e |
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