Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms
Unruptured intracranial aneurysm (UIA) is a life-threatening cerebrovascular condition. Here the authors report altered gut microbiota including low abundance of Hungatella hathewayi in patients with UIAs, and show that supplementation with Hungatella hathewayi or the metabolite taurine prevents UIA...
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Nature Portfolio
2020
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oai:doaj.org-article:a5d377b48fd84340b616882d21e986662021-12-02T16:05:51ZAlterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms10.1038/s41467-020-16990-32041-1723https://doaj.org/article/a5d377b48fd84340b616882d21e986662020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16990-3https://doaj.org/toc/2041-1723Unruptured intracranial aneurysm (UIA) is a life-threatening cerebrovascular condition. Here the authors report altered gut microbiota including low abundance of Hungatella hathewayi in patients with UIAs, and show that supplementation with Hungatella hathewayi or the metabolite taurine prevents UIAs in mice.Hao LiHaochen XuYouxiang LiYuhua JiangYamin HuTingting LiuXueqing TianXihai ZhaoYandong ZhuShuxia WangChunrui ZhangJing GeXuliang WangHongyan WenCongxia BaiYingying SunLi SongYinhui ZhangRutai HuiJun CaiJingzhou ChenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Hao Li Haochen Xu Youxiang Li Yuhua Jiang Yamin Hu Tingting Liu Xueqing Tian Xihai Zhao Yandong Zhu Shuxia Wang Chunrui Zhang Jing Ge Xuliang Wang Hongyan Wen Congxia Bai Yingying Sun Li Song Yinhui Zhang Rutai Hui Jun Cai Jingzhou Chen Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms |
| description |
Unruptured intracranial aneurysm (UIA) is a life-threatening cerebrovascular condition. Here the authors report altered gut microbiota including low abundance of Hungatella hathewayi in patients with UIAs, and show that supplementation with Hungatella hathewayi or the metabolite taurine prevents UIAs in mice. |
| format |
article |
| author |
Hao Li Haochen Xu Youxiang Li Yuhua Jiang Yamin Hu Tingting Liu Xueqing Tian Xihai Zhao Yandong Zhu Shuxia Wang Chunrui Zhang Jing Ge Xuliang Wang Hongyan Wen Congxia Bai Yingying Sun Li Song Yinhui Zhang Rutai Hui Jun Cai Jingzhou Chen |
| author_facet |
Hao Li Haochen Xu Youxiang Li Yuhua Jiang Yamin Hu Tingting Liu Xueqing Tian Xihai Zhao Yandong Zhu Shuxia Wang Chunrui Zhang Jing Ge Xuliang Wang Hongyan Wen Congxia Bai Yingying Sun Li Song Yinhui Zhang Rutai Hui Jun Cai Jingzhou Chen |
| author_sort |
Hao Li |
| title |
Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms |
| title_short |
Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms |
| title_full |
Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms |
| title_fullStr |
Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms |
| title_full_unstemmed |
Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms |
| title_sort |
alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/a5d377b48fd84340b616882d21e98666 |
| work_keys_str_mv |
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