Ionic liquids as capping agents of silver nanoparticles. Part II: Antimicrobial and cytotoxic study

This study was performed to validate the previous antimicrobial and cytotoxic data on the influence of ionic liquids as coatings of silver nanoparticles (AgNPs). The antibacterial and cytotoxicity assessments were carried out against different microorganisms and a cancerous cell line. AgNPs with two...

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Autores principales:	Gholami Ahmad, Shams Mahdi Sedigh, Abbaszadegan Abbas, Nabavizadeh Mohammadreza
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	silver nanoparticles antimicrobial alkyl chain charge surface modification Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/a5d5345fc3f2434c81cd1a1d97b405a7
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spelling	oai:doaj.org-article:a5d5345fc3f2434c81cd1a1d97b405a72021-12-05T14:10:50ZIonic liquids as capping agents of silver nanoparticles. Part II: Antimicrobial and cytotoxic study2191-955010.1515/gps-2021-0054https://doaj.org/article/a5d5345fc3f2434c81cd1a1d97b405a72021-09-01T00:00:00Zhttps://doi.org/10.1515/gps-2021-0054https://doaj.org/toc/2191-9550This study was performed to validate the previous antimicrobial and cytotoxic data on the influence of ionic liquids as coatings of silver nanoparticles (AgNPs). The antibacterial and cytotoxicity assessments were carried out against different microorganisms and a cancerous cell line. AgNPs with two different ionic-liquid coatings and hydrocarbon chains were synthesized and characterized. We tested the antibacterial activity of these NPs against Salmonella typhi, Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Candida albicans in planktonic forms and against Enterococcus faecalis and Escherichia coli in biofilm forms. MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay was employed for toxicity evaluation. The antimicrobial activity of NPs with 12 carbons was significantly higher than those with 18 carbons. Furthermore, NPs with 12 carbons were also effective against bacterial biofilms. All of the NPs tested had good cell viability at different antimicrobial concentrations. The length of the hydrocarbon chain is an essential factor in determining the antimicrobial activity of ionic-liquid-coated AgNPs. The variation in ionic-liquid coatings was not as effective as other influencing factors. Evaluation of AgNPs using other alkyl chain lengths to find the optimal size is recommended.Gholami AhmadShams Mahdi SedighAbbaszadegan AbbasNabavizadeh MohammadrezaDe Gruyterarticlesilver nanoparticlesantimicrobialalkyl chainchargesurface modificationChemistryQD1-999ENGreen Processing and Synthesis, Vol 10, Iss 1, Pp 585-593 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	silver nanoparticles antimicrobial alkyl chain charge surface modification Chemistry QD1-999
spellingShingle	silver nanoparticles antimicrobial alkyl chain charge surface modification Chemistry QD1-999 Gholami Ahmad Shams Mahdi Sedigh Abbaszadegan Abbas Nabavizadeh Mohammadreza Ionic liquids as capping agents of silver nanoparticles. Part II: Antimicrobial and cytotoxic study
description	This study was performed to validate the previous antimicrobial and cytotoxic data on the influence of ionic liquids as coatings of silver nanoparticles (AgNPs). The antibacterial and cytotoxicity assessments were carried out against different microorganisms and a cancerous cell line. AgNPs with two different ionic-liquid coatings and hydrocarbon chains were synthesized and characterized. We tested the antibacterial activity of these NPs against Salmonella typhi, Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Candida albicans in planktonic forms and against Enterococcus faecalis and Escherichia coli in biofilm forms. MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay was employed for toxicity evaluation. The antimicrobial activity of NPs with 12 carbons was significantly higher than those with 18 carbons. Furthermore, NPs with 12 carbons were also effective against bacterial biofilms. All of the NPs tested had good cell viability at different antimicrobial concentrations. The length of the hydrocarbon chain is an essential factor in determining the antimicrobial activity of ionic-liquid-coated AgNPs. The variation in ionic-liquid coatings was not as effective as other influencing factors. Evaluation of AgNPs using other alkyl chain lengths to find the optimal size is recommended.
format	article
author	Gholami Ahmad Shams Mahdi Sedigh Abbaszadegan Abbas Nabavizadeh Mohammadreza
author_facet	Gholami Ahmad Shams Mahdi Sedigh Abbaszadegan Abbas Nabavizadeh Mohammadreza
author_sort	Gholami Ahmad
title	Ionic liquids as capping agents of silver nanoparticles. Part II: Antimicrobial and cytotoxic study
title_short	Ionic liquids as capping agents of silver nanoparticles. Part II: Antimicrobial and cytotoxic study
title_full	Ionic liquids as capping agents of silver nanoparticles. Part II: Antimicrobial and cytotoxic study
title_fullStr	Ionic liquids as capping agents of silver nanoparticles. Part II: Antimicrobial and cytotoxic study
title_full_unstemmed	Ionic liquids as capping agents of silver nanoparticles. Part II: Antimicrobial and cytotoxic study
title_sort	ionic liquids as capping agents of silver nanoparticles. part ii: antimicrobial and cytotoxic study
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/a5d5345fc3f2434c81cd1a1d97b405a7
work_keys_str_mv	AT gholamiahmad ionicliquidsascappingagentsofsilvernanoparticlespartiiantimicrobialandcytotoxicstudy AT shamsmahdisedigh ionicliquidsascappingagentsofsilvernanoparticlespartiiantimicrobialandcytotoxicstudy AT abbaszadeganabbas ionicliquidsascappingagentsofsilvernanoparticlespartiiantimicrobialandcytotoxicstudy AT nabavizadehmohammadreza ionicliquidsascappingagentsofsilvernanoparticlespartiiantimicrobialandcytotoxicstudy
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Ionic liquids as capping agents of silver nanoparticles. Part II: Antimicrobial and cytotoxic study

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