Curdione and Schisandrin C Synergistically Reverse Hepatic Fibrosis via Modulating the TGF-β Pathway and Inhibiting Oxidative Stress
Hepatic fibrosis is the final pathway of several chronic liver diseases, which is characterized by the accumulation of extracellular matrix due to chronic hepatocyte damage. Activation of hepatic stellate cells and oxidative stress (OS) play an important role in mediating liver damage and initiating...
Saved in:
Main Authors: | Wenzhang Dai, Qin Qin, Zhiyong Li, Li Lin, Ruisheng Li, Zhie Fang, Yanzhong Han, Wenqing Mu, Lutong Ren, Tingting Liu, Xiaoyan Zhan, Xiaohe Xiao, Zhaofang Bai |
---|---|
Format: | article |
Language: | EN |
Published: |
Frontiers Media S.A.
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/a5e4b0dbbebf418cac2300267bcab8a7 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Schisandrin B Attenuates Hepatic Stellate Cell Activation and Promotes Apoptosis to Protect against Liver Fibrosis
by: Zhiman Li, et al.
Published: (2021) -
Neuroprotective effects of curdione against focal cerebral ischemia reperfusion injury in rats
by: Li XJ, et al.
Published: (2017) -
GPR37 promotes the malignancy of lung adenocarcinoma via TGF-β/Smad pathway
by: Wang Jian, et al.
Published: (2020) -
Downregulation of TGF-β1 suppressed proliferation and increased chemosensitivity of ovarian cancer cells by promoting BRCA1/Smad3 signaling
by: Wang,Yanqiu, et al.
Published: (2018) -
Schisandrin B Antagonizes Cardiotoxicity Induced by Pirarubicin by Inhibiting Mitochondrial Permeability Transition Pore (mPTP) Opening and Decreasing Cardiomyocyte Apoptosis
by: Hongwei Shi, et al.
Published: (2021)