Mtss1 promotes cell-cell junction assembly and stability through the small GTPase Rac1.

Mtss1 promotes cell-cell junction assembly and stability through the small GTPase Rac1.

Cell-cell junctions are an integral part of epithelia and are often disrupted in cancer cells during epithelial-to-mesenchymal transition (EMT), which is a main driver of metastatic spread. We show here that Metastasis suppressor-1 (Mtss1; Missing in Metastasis, MIM), a member of the IMD-family of p...

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Autores principales: John C Dawson, Susann Bruche, Heather J Spence, Vania M M Braga, Laura M Machesky
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a5e57de7038d49d480ef17bb33be33eb
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