Mtss1 promotes cell-cell junction assembly and stability through the small GTPase Rac1.

Cell-cell junctions are an integral part of epithelia and are often disrupted in cancer cells during epithelial-to-mesenchymal transition (EMT), which is a main driver of metastatic spread. We show here that Metastasis suppressor-1 (Mtss1; Missing in Metastasis, MIM), a member of the IMD-family of p...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: John C Dawson, Susann Bruche, Heather J Spence, Vania M M Braga, Laura M Machesky
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/a5e57de7038d49d480ef17bb33be33eb
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!