Dexamethasone and lactoferrin induced PMN-MDSCs relieved inflammatory adverse events of anti-cancer therapy without tumor promotion

Li et al. show that dexamethasone and lactoferrin induced polymorphonuclear myeloid-derived suppressor cells relieve inflammatory conditions in mouse models with minimal effect on tumour growth. This work demonstrates promise for combating inflammatory adverse events during anti-cancer treatments.

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Autores principales: Xing Li, Jie Chen, Yong-Jian Chen, Yi-Dan Qiao, Li-Yun Zhao, Nan Jiang, Xiang-Yuan Wu, Yan-Fang Xing
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a5f0da4bd4164d039b55198c4e4188a9
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spelling oai:doaj.org-article:a5f0da4bd4164d039b55198c4e4188a92021-12-02T15:52:58ZDexamethasone and lactoferrin induced PMN-MDSCs relieved inflammatory adverse events of anti-cancer therapy without tumor promotion10.1038/s42003-021-01769-z2399-3642https://doaj.org/article/a5f0da4bd4164d039b55198c4e4188a92021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01769-zhttps://doaj.org/toc/2399-3642Li et al. show that dexamethasone and lactoferrin induced polymorphonuclear myeloid-derived suppressor cells relieve inflammatory conditions in mouse models with minimal effect on tumour growth. This work demonstrates promise for combating inflammatory adverse events during anti-cancer treatments.Xing LiJie ChenYong-Jian ChenYi-Dan QiaoLi-Yun ZhaoNan JiangXiang-Yuan WuYan-Fang XingNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Xing Li
Jie Chen
Yong-Jian Chen
Yi-Dan Qiao
Li-Yun Zhao
Nan Jiang
Xiang-Yuan Wu
Yan-Fang Xing
Dexamethasone and lactoferrin induced PMN-MDSCs relieved inflammatory adverse events of anti-cancer therapy without tumor promotion
description Li et al. show that dexamethasone and lactoferrin induced polymorphonuclear myeloid-derived suppressor cells relieve inflammatory conditions in mouse models with minimal effect on tumour growth. This work demonstrates promise for combating inflammatory adverse events during anti-cancer treatments.
format article
author Xing Li
Jie Chen
Yong-Jian Chen
Yi-Dan Qiao
Li-Yun Zhao
Nan Jiang
Xiang-Yuan Wu
Yan-Fang Xing
author_facet Xing Li
Jie Chen
Yong-Jian Chen
Yi-Dan Qiao
Li-Yun Zhao
Nan Jiang
Xiang-Yuan Wu
Yan-Fang Xing
author_sort Xing Li
title Dexamethasone and lactoferrin induced PMN-MDSCs relieved inflammatory adverse events of anti-cancer therapy without tumor promotion
title_short Dexamethasone and lactoferrin induced PMN-MDSCs relieved inflammatory adverse events of anti-cancer therapy without tumor promotion
title_full Dexamethasone and lactoferrin induced PMN-MDSCs relieved inflammatory adverse events of anti-cancer therapy without tumor promotion
title_fullStr Dexamethasone and lactoferrin induced PMN-MDSCs relieved inflammatory adverse events of anti-cancer therapy without tumor promotion
title_full_unstemmed Dexamethasone and lactoferrin induced PMN-MDSCs relieved inflammatory adverse events of anti-cancer therapy without tumor promotion
title_sort dexamethasone and lactoferrin induced pmn-mdscs relieved inflammatory adverse events of anti-cancer therapy without tumor promotion
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a5f0da4bd4164d039b55198c4e4188a9
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AT jiechen dexamethasoneandlactoferrininducedpmnmdscsrelievedinflammatoryadverseeventsofanticancertherapywithouttumorpromotion
AT yongjianchen dexamethasoneandlactoferrininducedpmnmdscsrelievedinflammatoryadverseeventsofanticancertherapywithouttumorpromotion
AT yidanqiao dexamethasoneandlactoferrininducedpmnmdscsrelievedinflammatoryadverseeventsofanticancertherapywithouttumorpromotion
AT liyunzhao dexamethasoneandlactoferrininducedpmnmdscsrelievedinflammatoryadverseeventsofanticancertherapywithouttumorpromotion
AT nanjiang dexamethasoneandlactoferrininducedpmnmdscsrelievedinflammatoryadverseeventsofanticancertherapywithouttumorpromotion
AT xiangyuanwu dexamethasoneandlactoferrininducedpmnmdscsrelievedinflammatoryadverseeventsofanticancertherapywithouttumorpromotion
AT yanfangxing dexamethasoneandlactoferrininducedpmnmdscsrelievedinflammatoryadverseeventsofanticancertherapywithouttumorpromotion
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