Betahistine exerts a dose-dependent effect on cochlear stria vascularis blood flow in guinea pigs in vivo.
<h4>Objective</h4>Betahistine is a histamine H(1)-receptor agonist and H(3)-receptor antagonist that is administered to treat Menière's disease. Despite widespread use, its pharmacological mode of action has not been entirely elucidated. This study investigated the effect of betahis...
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Main Authors: | Fritz Ihler, Mattis Bertlich, Kariem Sharaf, Sebastian Strieth, Michael Strupp, Martin Canis |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/a60723b3a12e4f37b472a1ee81d11a66 |
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