Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy

Aim: to evaluate changes in the parameters of the visual system, psycho-physiological reactions (psychoemotional changes), and hormonal changes in patients with central serous chorioretinopathy and on this basis to develop a conceptual scheme for the activation of pathogenetic mechanisms of the form...

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Autores principales: A. A. Shchuko, S. I. Kolesnikov, T. N. Iurevа, A. N. Zlobina
Formato: article
Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2019
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Acceso en línea:https://doaj.org/article/a6127d241608426f9d0f05f7aa3dcd39
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spelling oai:doaj.org-article:a6127d241608426f9d0f05f7aa3dcd392021-11-23T06:14:42ZEvaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy2541-94202587-959610.29413/ABS.2019-4.4.18https://doaj.org/article/a6127d241608426f9d0f05f7aa3dcd392019-08-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/2132https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Aim: to evaluate changes in the parameters of the visual system, psycho-physiological reactions (psychoemotional changes), and hormonal changes in patients with central serous chorioretinopathy and on this basis to develop a conceptual scheme for the activation of pathogenetic mechanisms of the formation of acute and chronic forms of the disease. Material and methods. 40 people with central serous chorioretinopathy and 26 control subjects were examined with the assessment of psychophysiological (psychoemotional) and hormonal changes.Results. The most informative criteria have been identified which determine various forms of the clinical course of central serous chorioretinopathy: the area of damage to the retinal pigment epithelium, psycho-emotional changes (the difficulties of role-playing, dependence on other people in domestic and professional environment, a high degree of reactive and personal anxiety, paranoia and level of distress), violation of the psycho-physiological characteristics of the state of the visual system, changes in hormonal regulation (cortisol, thyroid hormones, dehydroepiandrosterone, melatonin, 17-OH-progesterone, testosterone).Conclusion. The complex of psychophysiological changes that form the basis for the pathogenesis of central serous chorioretinopathy, according to the feedback mechanism, enhances the initial moments of the disease, exacerbates the severity of clinical manifestations and leads to chronicity of the pathological process, causing, thus, the complexity of diagnosis and treatment of central serous chorioretinopathy.A. A. ShchukoS. I. KolesnikovT. N. IurevаA. N. ZlobinaScientific Сentre for Family Health and Human Reproduction Problemsarticlecentral serous chorioretinopathyvisual systempsycho-physiological reactionsendocrine changespsychoemotional changesdisease pathogenesisScienceQRUActa Biomedica Scientifica, Vol 4, Iss 4, Pp 119-123 (2019)
institution DOAJ
collection DOAJ
language RU
topic central serous chorioretinopathy
visual system
psycho-physiological reactions
endocrine changes
psychoemotional changes
disease pathogenesis
Science
Q
spellingShingle central serous chorioretinopathy
visual system
psycho-physiological reactions
endocrine changes
psychoemotional changes
disease pathogenesis
Science
Q
A. A. Shchuko
S. I. Kolesnikov
T. N. Iurevа
A. N. Zlobina
Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy
description Aim: to evaluate changes in the parameters of the visual system, psycho-physiological reactions (psychoemotional changes), and hormonal changes in patients with central serous chorioretinopathy and on this basis to develop a conceptual scheme for the activation of pathogenetic mechanisms of the formation of acute and chronic forms of the disease. Material and methods. 40 people with central serous chorioretinopathy and 26 control subjects were examined with the assessment of psychophysiological (psychoemotional) and hormonal changes.Results. The most informative criteria have been identified which determine various forms of the clinical course of central serous chorioretinopathy: the area of damage to the retinal pigment epithelium, psycho-emotional changes (the difficulties of role-playing, dependence on other people in domestic and professional environment, a high degree of reactive and personal anxiety, paranoia and level of distress), violation of the psycho-physiological characteristics of the state of the visual system, changes in hormonal regulation (cortisol, thyroid hormones, dehydroepiandrosterone, melatonin, 17-OH-progesterone, testosterone).Conclusion. The complex of psychophysiological changes that form the basis for the pathogenesis of central serous chorioretinopathy, according to the feedback mechanism, enhances the initial moments of the disease, exacerbates the severity of clinical manifestations and leads to chronicity of the pathological process, causing, thus, the complexity of diagnosis and treatment of central serous chorioretinopathy.
format article
author A. A. Shchuko
S. I. Kolesnikov
T. N. Iurevа
A. N. Zlobina
author_facet A. A. Shchuko
S. I. Kolesnikov
T. N. Iurevа
A. N. Zlobina
author_sort A. A. Shchuko
title Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy
title_short Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy
title_full Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy
title_fullStr Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy
title_full_unstemmed Evaluation of Psychophysiological and Hormonal Changes in Acute and Chronic Forms of Central Serous Chorioretinopathy
title_sort evaluation of psychophysiological and hormonal changes in acute and chronic forms of central serous chorioretinopathy
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2019
url https://doaj.org/article/a6127d241608426f9d0f05f7aa3dcd39
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AT sikolesnikov evaluationofpsychophysiologicalandhormonalchangesinacuteandchronicformsofcentralserouschorioretinopathy
AT tniureva evaluationofpsychophysiologicalandhormonalchangesinacuteandchronicformsofcentralserouschorioretinopathy
AT anzlobina evaluationofpsychophysiologicalandhormonalchangesinacuteandchronicformsofcentralserouschorioretinopathy
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