Telomeric repeats facilitate CENP-A(Cnp1) incorporation via telomere binding proteins.

Telomeric repeats facilitate CENP-A(Cnp1) incorporation via telomere binding proteins.

The histone H3 variant, CENP-A, is normally assembled upon canonical centromeric sequences, but there is no apparent obligate coupling of sequence and assembly, suggesting that centromere location can be epigenetically determined. To explore the tolerances and constraints on CENP-A deposition we inv...

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Autores principales: Araceli G Castillo, Alison L Pidoux, Sandra Catania, Mickaël Durand-Dubief, Eun Shik Choi, Georgina Hamilton, Karl Ekwall, Robin C Allshire
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/a61b08f39614411ca77ca840e45da6af
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