Trained Innate Immunity Induced by Vaccination with Low-Virulence <i>Candida</i> Species Mediates Protection against Several Forms of Fungal Sepsis via Ly6G <sup>+</sup> Gr-1 <sup>+</sup> Leukocytes

Trained innate immunity (TII) is induced following immunization with live attenuated microbes and represents a clinically important strategy to enhance innate defenses. TII was initially demonstrated following intravenous inoculation with low-virulence Candida albicansC. albicans

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Autores principales: Elizabeth A. Lilly, Breah E. Bender, Shannon Esher Righi, Paul L. Fidel, Mairi C. Noverr
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Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/a61cae03eb264d2db7290bf4dd4448bc
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spelling oai:doaj.org-article:a61cae03eb264d2db7290bf4dd4448bc2021-11-03T21:52:35Z Trained Innate Immunity Induced by Vaccination with Low-Virulence <i>Candida</i> Species Mediates Protection against Several Forms of Fungal Sepsis via Ly6G <sup>+</sup> Gr-1 <sup>+</sup> Leukocytes 2150-751110.1128/mBio.02548-21https://doaj.org/article/a61cae03eb264d2db7290bf4dd4448bc2021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02548-21https://doaj.org/toc/2150-7511 Trained innate immunity (TII) is induced following immunization with live attenuated microbes and represents a clinically important strategy to enhance innate defenses. TII was initially demonstrated following intravenous inoculation with low-virulence Candida albicansC. albicansElizabeth A. LillyBreah E. BenderShannon Esher RighiPaul L. FidelMairi C. NoverrAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Elizabeth A. Lilly
Breah E. Bender
Shannon Esher Righi
Paul L. Fidel
Mairi C. Noverr
Trained Innate Immunity Induced by Vaccination with Low-Virulence <i>Candida</i> Species Mediates Protection against Several Forms of Fungal Sepsis via Ly6G <sup>+</sup> Gr-1 <sup>+</sup> Leukocytes
description Trained innate immunity (TII) is induced following immunization with live attenuated microbes and represents a clinically important strategy to enhance innate defenses. TII was initially demonstrated following intravenous inoculation with low-virulence Candida albicansC. albicans
format article
author Elizabeth A. Lilly
Breah E. Bender
Shannon Esher Righi
Paul L. Fidel
Mairi C. Noverr
author_facet Elizabeth A. Lilly
Breah E. Bender
Shannon Esher Righi
Paul L. Fidel
Mairi C. Noverr
author_sort Elizabeth A. Lilly
title Trained Innate Immunity Induced by Vaccination with Low-Virulence <i>Candida</i> Species Mediates Protection against Several Forms of Fungal Sepsis via Ly6G <sup>+</sup> Gr-1 <sup>+</sup> Leukocytes
title_short Trained Innate Immunity Induced by Vaccination with Low-Virulence <i>Candida</i> Species Mediates Protection against Several Forms of Fungal Sepsis via Ly6G <sup>+</sup> Gr-1 <sup>+</sup> Leukocytes
title_full Trained Innate Immunity Induced by Vaccination with Low-Virulence <i>Candida</i> Species Mediates Protection against Several Forms of Fungal Sepsis via Ly6G <sup>+</sup> Gr-1 <sup>+</sup> Leukocytes
title_fullStr Trained Innate Immunity Induced by Vaccination with Low-Virulence <i>Candida</i> Species Mediates Protection against Several Forms of Fungal Sepsis via Ly6G <sup>+</sup> Gr-1 <sup>+</sup> Leukocytes
title_full_unstemmed Trained Innate Immunity Induced by Vaccination with Low-Virulence <i>Candida</i> Species Mediates Protection against Several Forms of Fungal Sepsis via Ly6G <sup>+</sup> Gr-1 <sup>+</sup> Leukocytes
title_sort trained innate immunity induced by vaccination with low-virulence <i>candida</i> species mediates protection against several forms of fungal sepsis via ly6g <sup>+</sup> gr-1 <sup>+</sup> leukocytes
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/a61cae03eb264d2db7290bf4dd4448bc
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AT breahebender trainedinnateimmunityinducedbyvaccinationwithlowvirulenceicandidaispeciesmediatesprotectionagainstseveralformsoffungalsepsisvialy6gsupsupgr1supsupleukocytes
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