Diagnostic and prognostic value of autoantibodies for diabetes mellitus. A novel T1D autoimmunity target - zinc transporter 8 (ZnT8)

The progressive loss of beta cells in Type 1 Diabetes (T1D) is a result of chronic autoimmune attack targeted at diverse molecules expressing in thepancreatic beta cells. The appearance of cellular and humoral autoimmunity precedes the clinical manifestation of T1D. There are several autoantigenswhi...

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Autores principales:	Olga Sergeevna Shapoval'yants, Tatiana Vasil'evna Nikonova
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2011
Materias:	type 1 mellitus diabetes autoantibodies immunnity zinc transporter 8 Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/a6218a47bb0248d9a764e34efe43e3ad
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spelling	oai:doaj.org-article:a6218a47bb0248d9a764e34efe43e3ad2021-11-14T09:00:16ZDiagnostic and prognostic value of autoantibodies for diabetes mellitus. A novel T1D autoimmunity target - zinc transporter 8 (ZnT8)2072-03512072-037810.14341/2072-0351-5629https://doaj.org/article/a6218a47bb0248d9a764e34efe43e3ad2011-06-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5629https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378The progressive loss of beta cells in Type 1 Diabetes (T1D) is a result of chronic autoimmune attack targeted at diverse molecules expressing in thepancreatic beta cells. The appearance of cellular and humoral autoimmunity precedes the clinical manifestation of T1D. There are several autoantigenswhich are supposed to be involved in pathogenesis of TD1. Zinc transporter 8 (ZnT8; Slc30A8) was identified as a novel T1D autoimmunitytarget.Olga Sergeevna Shapoval'yantsTatiana Vasil'evna NikonovaEndocrinology Research Centrearticletype 1 mellitus diabetesautoantibodiesimmunnityzinc transporter 8Nutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 14, Iss 2, Pp 18-22 (2011)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	type 1 mellitus diabetes autoantibodies immunnity zinc transporter 8 Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	type 1 mellitus diabetes autoantibodies immunnity zinc transporter 8 Nutritional diseases. Deficiency diseases RC620-627 Olga Sergeevna Shapoval'yants Tatiana Vasil'evna Nikonova Diagnostic and prognostic value of autoantibodies for diabetes mellitus. A novel T1D autoimmunity target - zinc transporter 8 (ZnT8)
description	The progressive loss of beta cells in Type 1 Diabetes (T1D) is a result of chronic autoimmune attack targeted at diverse molecules expressing in thepancreatic beta cells. The appearance of cellular and humoral autoimmunity precedes the clinical manifestation of T1D. There are several autoantigenswhich are supposed to be involved in pathogenesis of TD1. Zinc transporter 8 (ZnT8; Slc30A8) was identified as a novel T1D autoimmunitytarget.
format	article
author	Olga Sergeevna Shapoval'yants Tatiana Vasil'evna Nikonova
author_facet	Olga Sergeevna Shapoval'yants Tatiana Vasil'evna Nikonova
author_sort	Olga Sergeevna Shapoval'yants
title	Diagnostic and prognostic value of autoantibodies for diabetes mellitus. A novel T1D autoimmunity target - zinc transporter 8 (ZnT8)
title_short	Diagnostic and prognostic value of autoantibodies for diabetes mellitus. A novel T1D autoimmunity target - zinc transporter 8 (ZnT8)
title_full	Diagnostic and prognostic value of autoantibodies for diabetes mellitus. A novel T1D autoimmunity target - zinc transporter 8 (ZnT8)
title_fullStr	Diagnostic and prognostic value of autoantibodies for diabetes mellitus. A novel T1D autoimmunity target - zinc transporter 8 (ZnT8)
title_full_unstemmed	Diagnostic and prognostic value of autoantibodies for diabetes mellitus. A novel T1D autoimmunity target - zinc transporter 8 (ZnT8)
title_sort	diagnostic and prognostic value of autoantibodies for diabetes mellitus. a novel t1d autoimmunity target - zinc transporter 8 (znt8)
publisher	Endocrinology Research Centre
publishDate	2011
url	https://doaj.org/article/a6218a47bb0248d9a764e34efe43e3ad
work_keys_str_mv	AT olgasergeevnashapovalyants diagnosticandprognosticvalueofautoantibodiesfordiabetesmellitusanovelt1dautoimmunitytargetzinctransporter8znt8 AT tatianavasilevnanikonova diagnosticandprognosticvalueofautoantibodiesfordiabetesmellitusanovelt1dautoimmunitytargetzinctransporter8znt8
_version_	1718429600856408064

Diagnostic and prognostic value of autoantibodies for diabetes mellitus. A novel T1D autoimmunity target - zinc transporter 8 (ZnT8)

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