Dinucleoside polyphosphates act as 5′-RNA caps in bacteria
Nicotinamide adenine dinucleotide and coenzyme A serve as a 5′-cap of prokaryotic RNA. Here the authors report that methylated and non-methylated dinucleoside polyphosphates (Np n Ns) exist as Escherichia coli RNA caps which can be cleaved by 5′-pyrophosphohydrolase (RppH) and bis(5′-nucleosyl)-tetr...
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Nature Portfolio
2020
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oai:doaj.org-article:a626bb909a284b82ac5da5fc2819c2652021-12-02T15:37:09ZDinucleoside polyphosphates act as 5′-RNA caps in bacteria10.1038/s41467-020-14896-82041-1723https://doaj.org/article/a626bb909a284b82ac5da5fc2819c2652020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14896-8https://doaj.org/toc/2041-1723Nicotinamide adenine dinucleotide and coenzyme A serve as a 5′-cap of prokaryotic RNA. Here the authors report that methylated and non-methylated dinucleoside polyphosphates (Np n Ns) exist as Escherichia coli RNA caps which can be cleaved by 5′-pyrophosphohydrolase (RppH) and bis(5′-nucleosyl)-tetraphosphatase (ApaH).Oldřich HudečekRoberto BenoniPaul E. Reyes-GutierrezMartin CulkaHana ŠanderováMartin HubálekLubomír RulíšekJosef CvačkaLibor KrásnýHana CahováNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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Science Q Oldřich Hudeček Roberto Benoni Paul E. Reyes-Gutierrez Martin Culka Hana Šanderová Martin Hubálek Lubomír Rulíšek Josef Cvačka Libor Krásný Hana Cahová Dinucleoside polyphosphates act as 5′-RNA caps in bacteria |
description |
Nicotinamide adenine dinucleotide and coenzyme A serve as a 5′-cap of prokaryotic RNA. Here the authors report that methylated and non-methylated dinucleoside polyphosphates (Np n Ns) exist as Escherichia coli RNA caps which can be cleaved by 5′-pyrophosphohydrolase (RppH) and bis(5′-nucleosyl)-tetraphosphatase (ApaH). |
format |
article |
author |
Oldřich Hudeček Roberto Benoni Paul E. Reyes-Gutierrez Martin Culka Hana Šanderová Martin Hubálek Lubomír Rulíšek Josef Cvačka Libor Krásný Hana Cahová |
author_facet |
Oldřich Hudeček Roberto Benoni Paul E. Reyes-Gutierrez Martin Culka Hana Šanderová Martin Hubálek Lubomír Rulíšek Josef Cvačka Libor Krásný Hana Cahová |
author_sort |
Oldřich Hudeček |
title |
Dinucleoside polyphosphates act as 5′-RNA caps in bacteria |
title_short |
Dinucleoside polyphosphates act as 5′-RNA caps in bacteria |
title_full |
Dinucleoside polyphosphates act as 5′-RNA caps in bacteria |
title_fullStr |
Dinucleoside polyphosphates act as 5′-RNA caps in bacteria |
title_full_unstemmed |
Dinucleoside polyphosphates act as 5′-RNA caps in bacteria |
title_sort |
dinucleoside polyphosphates act as 5′-rna caps in bacteria |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/a626bb909a284b82ac5da5fc2819c265 |
work_keys_str_mv |
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