KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover

Inter-organelle signaling coordinates adaptive responses via currently unknown mechanisms. Here, Tapia et al. show that KDEL signaling repositions lysosomes in a complex process termed ‘traffic-induced degradation response for secretion’ (TIDeRS) that connects multiple pathways and Golgi secretion....

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Autores principales:	Diego Tapia, Tomás Jiménez, Constanza Zamora, Javier Espinoza, Riccardo Rizzo, Alexis González-Cárdenas, Danitza Fuentes, Sergio Hernández, Viviana A. Cavieres, Andrea Soza, Fanny Guzmán, Gloria Arriagada, María Isabel Yuseff, Gonzalo A. Mardones, Patricia V. Burgos, Alberto Luini, Alfonso González, Jorge Cancino
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a62da610b52144bab687c355e916d6aa
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spelling	oai:doaj.org-article:a62da610b52144bab687c355e916d6aa2021-12-02T17:01:37ZKDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover10.1038/s41467-019-08501-w2041-1723https://doaj.org/article/a62da610b52144bab687c355e916d6aa2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08501-whttps://doaj.org/toc/2041-1723Inter-organelle signaling coordinates adaptive responses via currently unknown mechanisms. Here, Tapia et al. show that KDEL signaling repositions lysosomes in a complex process termed ‘traffic-induced degradation response for secretion’ (TIDeRS) that connects multiple pathways and Golgi secretion.Diego TapiaTomás JiménezConstanza ZamoraJavier EspinozaRiccardo RizzoAlexis González-CárdenasDanitza FuentesSergio HernándezViviana A. CavieresAndrea SozaFanny GuzmánGloria ArriagadaMaría Isabel YuseffGonzalo A. MardonesPatricia V. BurgosAlberto LuiniAlfonso GonzálezJorge CancinoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Diego Tapia Tomás Jiménez Constanza Zamora Javier Espinoza Riccardo Rizzo Alexis González-Cárdenas Danitza Fuentes Sergio Hernández Viviana A. Cavieres Andrea Soza Fanny Guzmán Gloria Arriagada María Isabel Yuseff Gonzalo A. Mardones Patricia V. Burgos Alberto Luini Alfonso González Jorge Cancino KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover
description	Inter-organelle signaling coordinates adaptive responses via currently unknown mechanisms. Here, Tapia et al. show that KDEL signaling repositions lysosomes in a complex process termed ‘traffic-induced degradation response for secretion’ (TIDeRS) that connects multiple pathways and Golgi secretion.
format	article
author	Diego Tapia Tomás Jiménez Constanza Zamora Javier Espinoza Riccardo Rizzo Alexis González-Cárdenas Danitza Fuentes Sergio Hernández Viviana A. Cavieres Andrea Soza Fanny Guzmán Gloria Arriagada María Isabel Yuseff Gonzalo A. Mardones Patricia V. Burgos Alberto Luini Alfonso González Jorge Cancino
author_facet	Diego Tapia Tomás Jiménez Constanza Zamora Javier Espinoza Riccardo Rizzo Alexis González-Cárdenas Danitza Fuentes Sergio Hernández Viviana A. Cavieres Andrea Soza Fanny Guzmán Gloria Arriagada María Isabel Yuseff Gonzalo A. Mardones Patricia V. Burgos Alberto Luini Alfonso González Jorge Cancino
author_sort	Diego Tapia
title	KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover
title_short	KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover
title_full	KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover
title_fullStr	KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover
title_full_unstemmed	KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover
title_sort	kdel receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/a62da610b52144bab687c355e916d6aa
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KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover

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