Benign orbital tumors with bone destruction in children.

<h4>Purpose</h4>To present rare benign orbital tumors with bone destruction in children who could not be diagnosed pre-surgically and may simulate malignant ones.<h4>Methods</h4>A retrospective review of cases. Clinical, operative and pathological records in all children with...

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Autores principales:	Jianhua Yan, Sheng Zhou, Yongping Li
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a633d806e3b840edb0e6f2dae9bb354f
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spelling	oai:doaj.org-article:a633d806e3b840edb0e6f2dae9bb354f2021-11-18T07:26:48ZBenign orbital tumors with bone destruction in children.1932-620310.1371/journal.pone.0032111https://doaj.org/article/a633d806e3b840edb0e6f2dae9bb354f2012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22384155/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Purpose</h4>To present rare benign orbital tumors with bone destruction in children who could not be diagnosed pre-surgically and may simulate malignant ones.<h4>Methods</h4>A retrospective review of cases. Clinical, operative and pathological records in all children with a diagnosis of benign orbital tumors who showed remarkable bone destruction at a tertiary Ophthalmic Center in China between Jan 1, 2000 and Dec 31, 2009 were reviewed. All patients had definitive histopathologic diagnosis.<h4>Results</h4>Eight patients with benign orbital tumors showed obvious bone destruction, including six cases of eosinophilic granuloma, one case of leiomyoma and one case of primary orbital intraosseous hemangioma. Among them, three patients were females and five patients were males. Tumors were unilateral in all cases, with both the right and left side affected equally. Age ranged from 3 to 7 years (mean 4.1 years). Symptom duration ranged from 1 to 5 weeks (mean 4.8 weeks). Eyelid swelling and palpable mass were the most common complaint. There was no evidence for multifocal involvement in cases with eosinophilic granuloma. Among six patients with eosinophilic granuloma, two were treated with low dose radiation (10 Gy), three received systemic corticosteroid and one was periodically observed only after incisional biopsy or subtotal curettage. There was no postoperative therapeutic intervention in the two patients with leiomyoma and intraosseous hemangioma. All eight patients regained normal vision without local recurrence after a mean follow-up time of 32.8 months.<h4>Conclusion</h4>Benign orbital tumors such as isolated eosinophilic granuloma, leiomyoma and primary orbital intraosseous hemangioma may show remarkable bone destruction.Jianhua YanSheng ZhouYongping LiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 2, p e32111 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jianhua Yan Sheng Zhou Yongping Li Benign orbital tumors with bone destruction in children.
description	<h4>Purpose</h4>To present rare benign orbital tumors with bone destruction in children who could not be diagnosed pre-surgically and may simulate malignant ones.<h4>Methods</h4>A retrospective review of cases. Clinical, operative and pathological records in all children with a diagnosis of benign orbital tumors who showed remarkable bone destruction at a tertiary Ophthalmic Center in China between Jan 1, 2000 and Dec 31, 2009 were reviewed. All patients had definitive histopathologic diagnosis.<h4>Results</h4>Eight patients with benign orbital tumors showed obvious bone destruction, including six cases of eosinophilic granuloma, one case of leiomyoma and one case of primary orbital intraosseous hemangioma. Among them, three patients were females and five patients were males. Tumors were unilateral in all cases, with both the right and left side affected equally. Age ranged from 3 to 7 years (mean 4.1 years). Symptom duration ranged from 1 to 5 weeks (mean 4.8 weeks). Eyelid swelling and palpable mass were the most common complaint. There was no evidence for multifocal involvement in cases with eosinophilic granuloma. Among six patients with eosinophilic granuloma, two were treated with low dose radiation (10 Gy), three received systemic corticosteroid and one was periodically observed only after incisional biopsy or subtotal curettage. There was no postoperative therapeutic intervention in the two patients with leiomyoma and intraosseous hemangioma. All eight patients regained normal vision without local recurrence after a mean follow-up time of 32.8 months.<h4>Conclusion</h4>Benign orbital tumors such as isolated eosinophilic granuloma, leiomyoma and primary orbital intraosseous hemangioma may show remarkable bone destruction.
format	article
author	Jianhua Yan Sheng Zhou Yongping Li
author_facet	Jianhua Yan Sheng Zhou Yongping Li
author_sort	Jianhua Yan
title	Benign orbital tumors with bone destruction in children.
title_short	Benign orbital tumors with bone destruction in children.
title_full	Benign orbital tumors with bone destruction in children.
title_fullStr	Benign orbital tumors with bone destruction in children.
title_full_unstemmed	Benign orbital tumors with bone destruction in children.
title_sort	benign orbital tumors with bone destruction in children.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/a633d806e3b840edb0e6f2dae9bb354f
work_keys_str_mv	AT jianhuayan benignorbitaltumorswithbonedestructioninchildren AT shengzhou benignorbitaltumorswithbonedestructioninchildren AT yongpingli benignorbitaltumorswithbonedestructioninchildren
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Benign orbital tumors with bone destruction in children.

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